GLYCOBIOLOGY MARKET ANALYSIS | Coherent Market Insights

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• GLYCOBIOLOGY MARKET ANALYSIS
• Glycobiology Market, By Product Type
  (Instruments, Enzymes, Consumables, Reagents
  Kits), By Enzymes (Galactosidase (Fucosidases,
  Chitinases, Acetylgalactosaminidase, Heparinase,
  PNGase F, Others), GlcNAc Transferases
  (Acetylglucosaminyltransferase, Exostosin,
  Others), Fucosyltransferases, GalNAc
  Transferases, Galactosyl Transferases,
  Glucuronosyltransferases, Glucosyltransferases,
  Pentosyltransferases, Carbohydrate Kinases,
  Neuraminidases, Sialyltransferases, Others), By
  Application (Drug Discovery and Development
  Diagnostic Applications (Oncology, Immunology,
  Others), Industrial Application Therapeutic
  Application (Oncology, Immunology, Others),
  Others), By End User (Biopharmaceutical
  Companies, Research Laboratories, Hospitals,
  Diagnostic Centers, Contract Research
  Organizations, Biotechnology Industries, Academic
  Institutes, Others), and By Region (North
  America, Latin America, Europe, Asia Pacific,
  Middle East Africa) - Size, Share, Outlook, and
  Opportunity Analysis, 2019 - 2027

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• The term glycobiology is a branch of biology that
  deals with study of structure, function, and
  biosynthesis of saccharides (carbohydrates and
  carbohydrates containing molecules).
  Glycoconjugates is the general classification for
  carbohydrates covalently linked with other
  chemical species such as proteins, peptides,
  lipids and saccharides. Glycoconjugates and
  polysaccharides play a vital structural role in
  connective tissues.
• Global Glycobiology Market Drivers
• Glycans impact tumor proliferation, hematogenous
  metastasis, invasion and angiogenesis. Therefore,
  increasing prevalence of cancer is expected to
  propel growth of the global glycobiology market
  over the forecast period. For instance, according
  to the World Health Organization, around 18.1
  million new cases and 9.6 million deaths were
  registered due to cancer worldwide in 2018.
• Moreover, high incidence of HIV/AIDS is also
  expected to aid in growth of the market. For
  instance, according to Joint United Nations
  Program on HIV/AIDS, 37.9 million people globally
  were living with HIV at the end of 2018.

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• Global Glycobiology Market Restraints
• Complex structure of glycans is expected to
  hinder growth of the global glycobiology market.
  Unlike DNA or proteins, glycans do not have
  linear structure. Conventional sequence
  comparison methods cannot be applied directly to
  glycan comparison as structure and mechanism of
  glycans are completely different from DNA or
  proteins, which makes it more complex for
  analyzing. DNA or proteins have template
  sequences to synthesize primary structure, which
  are uniquely identified by template sequences.
  However, glycans do not have a template
  structure. Structure of glycan is determined by
  substrate specificity of glycosyl-transferases.
• Moreover, high costs of spectrometry and high
  performance liquid chromatography are also
  expected to limit growth of the market.

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• Global Glycobiology Market Opportunities
• RD in glycans is expected to offer lucrative
  growth opportunities for players in the global
  glycobiology market. For instance, in February
  2020, researchers from University of Minho,
  Portugal, reported development of a
  neurocompatible strategy to image temporal
  distribution of glycoproteins during neuronal
  development using Cu-free click chemistry.
• Moreover, increasing focus on manufacturing
  anti-cancer drugs is also expected to aid in
  growth of the market. For instance, in January
  2020, researchers from Universidade do Porto,
  Portugal, reported assessment of the role of
  O-glycosylation using glycoengineered gastric
  cancer models in the detection of CD44v9 a
  major protein splice variant isoforms expressed
  in human gastrointestinal cancer cellsby
  monoclonal antibodies.
• Enzymes segment in the global glycobiology market
  was valued at US 487.1 Mn in 2019 and is
  expected to reach US 1,371.0 Mn by 2027 at a
  CAGR of 13.6 during the forecast period.

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Market Trends/Key Takeaways

• Increasing adoption of viscosupplementation and
  facial aesthetic using hyaluronic acid is aiding
  growth of the market. Hyaluronan, a natural
  occurring glycosaminogen, is used in
  viscosupplementation and tissue fillers for
  volume restoration in facial rejuvenation.
• Replacement of conventional glycoanalysis
  approaches with advanced techniques is also
  boosting growth of the market. Conventional
  methods for analysis of glycoforms in complex
  glycoproteins such as gel electrophoresis and
  elemental analysis are rapidly getting replaced
  by new approaches such as nuclear magnetic
  resonance (NMR) spectroscopy and mass
  spectrometry (MS).

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Global Glycobiology Market Competitive Landscape

• Major players operating in the global
  glycobiology market include, Merck KGaA,
  Bio-Techne Corporation, Bruker Corporation,
  Thermo Fisher Scientific, Inc., Shimadzu
  Corporation, Plexera Bioscience LLC, New England
  Biolabs Inc., Agilent Technologies, Inc., and
  ProZyme, Inc.
• Global Glycobiology Market Key Developments
• Major players in the market are focused on
  adopting various marketing strategies to expand
  their customer base. For instance, in February
  2020, New England Biolabs demonstrated its next
  generation sequencing portfolio at 2020 Advances
  in Genome Biology and Technology (AGBT) General
  Meeting, held in the U.S.
• Players in the market are also focused on
  adopting partnership strategies to expand their
  product portfolio. For instance, in November
  2019, MOBILion Systems, Inc. partnered with
  researchers at the University of Georgia, for RD
  in glycans and glycoproteins.

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