Rituxirel 500mg injection - PowerPoint PPT Presentation

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Rituxirel 500mg injection

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Rituxirel is an anticancer medicine which prevents the growth and spread of cancer cells in the body. – PowerPoint PPT presentation

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Title: Rituxirel 500mg injection


1
Rituxirel 500mg Injection Rituximab Uses Side
effects
  • MILLION HEALTH PHARMACEUTICALS

2
DESCRIPTION
  • Rituxirel 500mg is an anticancer medicine which
    prevents the growth and spread of cancer cells in
    the body.
  •  Rituxirel 500mg injection also indicated for the
    treatment of Non- Hodgkins lymphoma or chronic
    lymphocytic and with combination with another
    anticancer drugs like methotrexate is used for
    rheumatoid arthritis symptoms in adult treatment
  • Rituxirel 500mg with steroid regimen combination
    is given for the treatment of some rare disorders
    which cause blood vessels and other tissues
    inflammation in the body.

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INDICATION
  • Rituxirel 500mg and hyaluronidase human injection
    are given alone or combination with other drugs
    to treat certain types of non-Hodgkin's lymphoma
    and chronic lymphocytic leukemia (cancer start in
    WBC).
  • Rituxirel 500mg injection is also used with
    methotrexate (Otrexup, Rasuvo, Xatmep, others)
    for the treatment rheumatoid arthritis symptoms
    in adults that have been already treated with
    some type of regimen known as tumor necrosis
    factor (TNF) inhibitor. 

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MECHANISM OF ACTION
  • Rituxirel 500mg injection is a type of class
    called as monoclonal antibody and which is a new
    type of "targeted" cancer treatment and an
    integral part of the body's immune system. 
  • Rituxirel 500mg works by linking to the CD20
    antigen on normal and malignant B-cells. Hence
    the body's essential immune security is initiated
    to attack and kill the marked B-cells.

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PRODUCT DETAILS
  • RITUXIREL 500mg
  • Brand Rituxirel 
  • Ingredients Rituximab 
  • Strength 500mg 
  • Manufactured Reliance Life sciences
  • Package 100mg in a 1vial

7
PHARMACOKINETICS
  • ABSORPTIONNot availableDISTRIBUTIONvolume of
    distribution is 3.1 LMETABOLISMRituxirel
    500mg metabolized by human antimurine antibody
    production.EXCRETIONNot availableThe
    half-life of NHL is 22 days and for RA is 18.0
    days, GPA and microscopic polyangiitis is 23 days.

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DOSAGE MANAGEMENT
  • Rituxirel 500mg injection is recommended to
    administer only through intravenous infusion not
    by IV push or bolus.
  • ADMINISTRTION Take an Rituxirel 500mg
    injection amount and diluted to final
    concentration of 1 mg/ml up to 4 mg/ml as
    infusion (containing either 0.9 Nacl or 5
    dextrose in water). Invert gently the bag and mix
    the solution. Dispose unused drug left in vial.

9
PRECAUTIONS
  • Allergic condition against Rituxirel 500mg or any
    other medication informs your doctor.
  • While using Rituxirel 500mg injection do not take
    any vaccination or immunization without taking
    advice from doctors.
  • Avoid use of Rituxirel 500mg if you are pregnant.
    It will harm the baby unborn, while using
    Rituxirel 500mg use correct birth control to
    prevent pregnancy and for at least 2 weeks after
    your treatment ends. Rituxirel 100mg may affect
    the ability to have children in women. Inform
    your doctor if you planning to pregnant.

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SIDE EFFECTS
  • Common effectsfever and chills (flu like
    symptoms)
  • Less common side effectsWeakness nausea
    headache cough dyspnea pharyngitis

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DRUG INTERACTION
  • Rituxirel 500mg injection drug interaction has
    limited data is available at present.
  • Combination with fludarabine or cyclophosphamide
    has no effects in pharmacokinetics in CLL
    patients.Combination with methotrexate had no
    effects in pharmacokinetics.

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CONTRAINDICATIONS
  • Hypersensitivity or murine proteins. Active
    severe infections in rheumatoid arthritis
    Uncontrolled cardiac disease.

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PREGNANCY
  • Category C animal studies reproduction shown an
    adverse effect on the fetus. The drug has no
    enough and well controlled studies in humans,
    using in pregnant women benefits by warrant use
    of the drug.

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LACTATION
  • Rituxirel 500mg excreted into human milk is
    unknown. Due to the drug belongs to large protein
    molecule, no information is available. Women
    should not breast feed during Rituxirel
    500mg injection treatment and 12 months following
    last dose.

15
STORAGE
  • Store at 20C 30C Use the drug before
    expiry date Protected from direct sunlight Do
    not freeze or shake. Keep away from the
    childrens Discard the unused drug by asking
    the advice from doctor or pharmacist.

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MISSED DOSE
  • If a dose missed to take at the time then have it
    suddenly before next dose timing, if time reach
    for next dose, then skip missed dose and continue
    and continue the regular schedule. Do not have 2
    doses at a same time.

17
OVERDOSAGE
  • If the patients had high dose of Rituxirel
    500mg then seek immediately to the emergency
    department or poison control help line. Please
    consult the doctor for further clarification.

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CONTACT US
  • EMAIL ID  millionhealthpharmaceuticals_at_gmail.com
  • PHONE NO  91-9940472902
  • WEBSITE URL  https//millionpharma.com/rituxirel-
    500mg.php
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