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Enfiera 100mg Injection

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Title: Enfiera 100mg Injection


1
Enfiera 100mg injection Rituximab MHP
  • MILLION PHARMACEUTICALS

2
DESCRIPTION
  • Enfiera 100mg is an anticancer medicine which
    prevents the growth and spread of cancer cells in
    the body. Enfiera 100mg injection also indicated
    for the treatment of Non- Hodgkins lymphoma or
    chronic lymphocytic and with combination with
    another anticancer drugs like methotrexate is
    used for rheumatoid arthritis symptoms in adult
    treatment. 
  • Enfiera100mg with steroid regimen combination is
    given for the treatment of some rare disorders
    which cause blood vessels and other tissues
    inflammation in the body.

3
INDICATION
  • Enfiera 100mg and hyaluronidase human injection
    are given alone or combination with other drugs
    to treat certain types of non-Hodgkin's lymphoma
    and chronic lymphocytic leukemia (cancer start in
    WBC).Enfiera 100mg injection is also used with
    methotrexate (Otrexup, Rasuvo, Xatmep, others)
    for the treatment rheumatoid arthritis symptoms
    in adults that have been already treated with
    some type of regimen known as tumor necrosis
    factor (TNF) inhibitor. 

4
MECHANISM OF ACTION
  • Enfiera 100mg injection is a type of class called
    as monoclonal antibody and which is a new type of
    "targeted" cancer treatment and an integral part
    of the body's immune system. Naturally the body
    build antibodies in along with to an antigen
    which has entered the body and attach to the
    antigen for destruction by the immune system.

5
NON HODGKINS LYMPHOMA
6
PRODUCT DETAILS
  • Brand Enfiera
  • Ingredients Rituximab 
  • Strength 100mg 
  • Manufactured Biochem Pharmaceuticals Industries
  • Package 50ml in a 1vial

7
PHARMACOKINETICS
  • ABSORPTIONNot availableDISTRIBUTIONvolume
    of distribution is 3.1 LMETABOLISMEnfiera
    100mg injection metabolized by human antimurine
    antibody production.
  • EXCRETIONnot available
  • The half-life of NHL is 22 days and for RA is
    18.0 days, GPA and microscopic polyangiitis is 23
    days.

8
DOSAGE MANAGEMENT
  • Enfiera 100mg is recommended to administer only
    through intravenous infusion not by IV push or
    bolus.
  • ADMINISTRTION
  • Take an Enfiera 100mg amount and diluted to final
    concentration of 1 mg/ml up to 4 mg/ml as
    infusion (containing either 0.9 Nacl or 5
    dextrose in water). Invert gently the bag and mix
    the solution. Dispose unused drug left in vial.

9
PRECAUTIONS
  • Allergic condition against Enfiera 100mg
    injection or any other medication informs your
    doctor.Concerning your history of drug used
    which include in prescription, non-prescription,
    vitamins supplements, nutritional products just
    inform the doctor.While using Enfiera 100mg do
    not take any vaccination or immunization without
    taking advice from doctors.

10
SIDE EFFECTS
  • Common effectsfever and chills (flu like
    symptoms)Less common side effectsWeakness
    nausea headache cough dyspnea pharyngitis

11
DRUG INTERACTION
  • Enfiera 100mg injection drug interaction has
    limited data is available at present.Combination
    with fludarabine or cyclophosphamide has no
    effects in pharmacokinetics in CLL
    patients.Combination with methotrexate had no
    effects in pharmacokinetics.

12
CONTRAINDICATIONS
  • Hypersensitivity or murine proteins.Active
    severe infections in rheumatoid
    arthritisUncontrolled cardiac disease.

13
PREGNANCY
  • Category C animal studies reproduction shown an
    adverse effect on the fetus. The drug has no
    enough and well controlled studies in humans,
    using in pregnant women benefits by warrant use
    of the drug.

14
LACTATION
  • Enfiera 100mg excreted into human milk is
    unknown. Due to the drug belongs to large protein
    molecule, no information is available. Women
    should not breast feed during Enfiera 100mg
    injection treatment and 12 months following last
    dose.

15
STORAGE
  • Store at 20C 30C Use the drug before
    expiry date Protected from direct sunlight Do
    not freeze or shake. Keep away from the
    childrens Discard the unused drug by asking
    the advice from doctor or pharmacist.

16
MISSED DOSE
  • If a dose missed to take at the time then have it
    suddenly before next dose timing, if time reach
    for next dose, then skip missed dose and continue
    and continue the regular schedule. Do not have 2
    doses at a same time.

17
OVERDOSAGE
  • If the patients had high dose of Enfiera
    100mg then seek immediately to the emergency
    department or poison control help line. Please
    consult the doctor for further clarification.

18
CONTACT US
  • EMAIL ID
  • millionhealthpharmaceuticals_at_gmail.com
  • PHONE NO
  • 91-9940472902
  • WEBSITE URL https//millionpharma.com/enfiera-100m
    g.php
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