Quality Of Water In Pharmaceutical Industry

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Quality of water in pharmaceutical industry
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• Water is a key element for numerous
  pharmaceutical and life sciences processes. As a
  raw material, water is used in processing,
  formulation and manufacturing various
  pharmaceutical products and active pharmaceutical
  ingredients (API). Most industries rely majorly
  on surface water and groundwater sources for
  their pharmaceutical purposes. In its natural
  state, water from these sources is not free from
  contamination and needs to be purified before
  industries use it for pharmaceutical
  purposes.This process of water purification
  involves distillation and deionization that
  reduces the concentration of contaminated
  particles, parasites, bacteria, algae, viruses,
  and fungi. It is imperative that water is treated
  using proper procedures to ensure its
  purity.Depending on the route of administration
  of the pharmaceutical product, different grades
  of water quality are required. Based on water
  quality, below are different types of water for
  pharmaceutical use purposes.
• 1. Drinking waterDrinking water can be best
  described as Potable water. It may be sourced
  from a public water utility, a private water
  supply (e.g., a well) or a combination of both.
  Drinking water is the minimum quality of water
  that ought to be used for the preparation of
  official substances and other bulk pharmaceutical
  substances. The treatment required to make it
  safe for human consumption is determined post
  evaluating the condition of the source water.
  Drinking water, free from contamination is used
  for cleaning pharmaceutical manufacturing
  equipment and product-contact components. Some
  common methods of treatment include
  desalinization, softening, deionization, particle
  reduction, and reduction of inorganic and/or
  organic materials.The equipment and systems used
  to produce drinking water, their storage tanks,

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• distribution pipeworks and the water
  quality itself need to be routinely monitored for
  environmental, seasonal or supply changes which
  may affect the integrity of the water systems in
  place. Additionally, techniques such as back
  flushing, chemical and /or thermal sanitization
  should be put in place to tackle recontamination
  of water.
• 2. Purified Water Purified water is used mainly
  as an excipient in the production of
  non-parenteral administrations and in other
  pharmaceutical applications. Non-parenteral is
  most commonly referred to as the route that oral
  medications are administered, therefore it is of
  utmost importance that water used for
  non-parenteral preparations must meet the
  requirements for ionic and organic chemical
  purity.Purified water is generally produced by
  ion exchange, reverse osmosis, and
  ultrafiltration. While producing purified water
  it is important to protect it from
  recontamination and other microbial protection.
  Water treatment company provides sterile plant in
  pharmaceutical industry which is useful.