Cryopreservation / Sperm / Embryo Freezing

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Cryopreservation / Sperm / Embryo Freezing
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Cryopreservation / Sperm / Embryo Freezing
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Embryos, eggs and sperm can be preserved for
future use by cryopreservation (freezing). Cryopr
eservation of embryos is often used when there
are more embryos than needed for a fresh IVF
transfer. Embryo cryopreservation can provide an
additional opportunity for pregnancy, through
Frozen Embryo Transfer (FET), without undergoing
another ovarian stimulation and retrieval.
Embryos that meet developmental criteria for
appearance and rate of growth can be frozen at
any of several stages in their development. The
freezing process is computer controlled and
employs special solutions to protect the
fertilized eggs from damage. Frozen embryos are
stored at approximately -400F and can remain
viable for long periods of time. The survival
rate of frozen embryos is now 90 to 95 percent.
In addition, the rate of pregnancy using
cryopreserved embryos is similar to the rate when
using fresh embryos. There is no known increase
in the rate of spontaneous miscarriages or in the
rate of birth defects from pregnancies that have
resulted from the implantation of previously
frozen and thawed embryos.
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Sperm can be cryopreserved and stored for use
during an IUI or IVF cycle. All donor sperm is
cryopreserved and quarantined for a period of six
months to confirm that the donor does not carry
any viral diseases. As with embryos, some sperm
do not survive cryopreservation and
thawing. Until recently, egg freezing was
considered an experimental treatment. This was
because there was not enough data to predict if
there would be harm to children born through this
method and because earlier pregnancy rates using
frozen eggs were quite low. Thus far, the data
suggest children born from frozen eggs have
turned out fine. They also suggest that using
vitrification (a specialized freezing technique)
for egg freezing results in much higher pregnancy
ratessimilar to those of IVF treatment. Egg
freezing is often used by women wishing to
preserve their fertility and family building
options.
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