Hepatitis B treatment with Entecavir

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Hepatitis B Treatment with Entecavir
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What is Baraclude/Entecavir?   Baraclude (generic
Entecavir) is a antiviral medication that is
commonly used for the treatment of Hepatitis B
specially with patients who have liver damage.
This medication is not limited to treating
hepatitis B, but it is also used for the
treatment of HIV/AIDS and HBV infection.
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How does Entecavir works?   Baraclude is a
reverse transcript inhibitor whose main function
is to prevent the hepatitis B virus from
multiplying, thus reducing the hepatitis B virus
in the body. Although entecavir reduces the
hepatitis B virus, but it is not a cure for the
disease. Entecavir doesnt prevent liver damage
or reduces the risk of developing liver cancer.
Entecavir Cost
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• Entecavir Side effects
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• Mild
• Fever
• Infection
• Headache
• Fatigue
• Dyspepsia
• Vomiting
• Nausea
• Diarrhea
• Drowsiness
• Insomnia
• Abdominal Pain
• Dizziness
• Rash
• Alopecia

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• Moderate
• Peripheral Edema
• Ascites
• Elevated Hepatic Enzymes
• Hematuria
• Glycosuria
• Hyperglycemia
• Hyperbilirubinemia
• Hypoalbuminemia
• Thrombocytopenia
• Steatosis
• Hepatomegaly

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• Severe
• Hepatic Encephalopathy
• Hepatitis B Exacerbation
• Renal Failure (Unspecified)
• Anaphylactoid Reactions
• Lactic Acidosis
• Hepatotoxicity

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Efficacy of Entecavir According to a study,
Baraclude (generic Entecavir) had an unexpected
lower incidence of hepatocellular carcinoma in
the patients suffering from hepatitis B. Also,
it was observed that treatment with Entecavir led
to 64 lower incidence of HCC among the patients
who were suffering from chronic hepatitis B
without cirrhosis.
Baraclude Price
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In order to evaluate the impact of Entecavir
(Brand Baraclude) with antiviral therapy on HCC
Development, the study used the Risk Estimation
of HCC in chronic Hepatitis B model. This model
provides virtual control group of patients whose
HCC incidence is calculated based on the clinical
variables availability. 841 patients were
enrolled in this study But at the end data from
total of 646 patients were analysed. Among
these 646 patients, 420 were male, 542 were
Asians and 232 were positive for hepatitis B e
antigen.
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During the study, 17 patients were diagnosed with
HCC- of which 8 patients were suffering from
cirrhosis and 9 patients were not suffering from
cirrhosis. During the first year of the study, 3
patients developed HCC without cirrhosis, whereas
the REACH-B model in the first year estimated 4.7
cases. This led to a standardised ratio of
0.64. But this ratio had fallen to 0.37 during
the 4 years of the study.
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HCC incidence was lower than predicted, when the
results were compared between patients with and
without cirrhosis. REACH-B model predicted 30.2
cases of HCC incidence during 8.2 years of follow
up. But the actual figures were almost half 17
cases. This showed HCC incidence was lower than
predicted.
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In the end it was observed by the researchers
that Entecavir antiviral therapy is associated
with lower cases of HCC incidence. Although,
the risk of HCC still persisted in the chronic
hepatitis B patients. Vigilant surveillance
remain warranted in HCC patients regardless of
their reaction/response to Entecavir antiviral
treatment.
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Who should not take Entecavir treatment? Patients
who are allergic to Entecavir (Brand Baraclude)
are advised not to take this medication. Also
it is very important to clarity on your HIV
status, because this medication can significantly
complicate the treatment for HIV. If you have an
untreated or unrecognised HIV infection, do not
start this medication without consulting an
infectious disease specialist.
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This medication comes in 2 forms Oral tablets
and Oral solution i.e. Entecavir 0.5 mg and
Baraclude 1 mg and Baraclude 0.5 mg / ml. The
information provided on the page is meant for the
purpose of being helpful and educational. It
should not be considered as medical
advice.   Baraclude, entecavir, entecavir side
effects, baraclude generic, entecavir 0.5 mg,
baraclude 1mg, entecavir cost
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