How to Solve Melanoma Tumor Heterogeneity

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Creative Biolabs
How to Solve Melanoma Tumor Heterogeneity
https//www.creative-biolabs.com/adc/
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Background
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An important signaling pathway in melanoma.
Mutations in the BRAF gene promote tumor cell
proliferation.
The BRAF/MEK inhibitor combination therapy
developed for this target is the current standard
of care and is usually effective for melanoma
patients
BRAF signaling pathway
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Recent Study
The researchers found that a lots of tumor cells
that are resistant to BRAF/MEK inhibitors are
able to express a highly receptor tyrosine kinase
known as AXL on the cell surface. Therefore, the
development of AXL-targeted therapeutic
approaches has naturally become the goal of their
research for a long time.
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Reserach results
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Reserach results
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Conclusions
This study shows that AXL-107-MMAE therapy is
worthy of being further tested in clinical trials
on its potential in treating cancer patients who
have never received treatment or have developed
resistance to other therapies, whether as a
monotherapy or combination therapy. Despite these
unidentified factors, the antibody durg
conjugates therapy still plays a significant role
in the field of cancer treatment around the world
and will bring great treating effects for a huge
amount of patients who suffering for a variety of
diseases. We expect these new results will
further advance the development of this therapy
and bring new treatment options to these patients
as soon as possible.
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Established in 2004, Creative Biolabs is highly
specialized in advanced antibody biochemistry and
engineering, including ADC customs products. With
more than a decade of exploration and expansion,
our current research and service capacity covers
the entire new drug discovery and antibody
conjugation service, which ranges from early
discovery, pre-clinical evaluations, cGMP
manufacturing, dar conjugation to clinical
trials. As an international cooperation, Creative
Biolabs has established multiple offices all
around the globe with more than 200 well-trained
full-time scientists and technicians, who work
closely with our customers and research partners
to develop new medicines for a better, healthier
world.
Creative Biolabs
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Contact Us
45-1 Ramsey Road, Shirley, NY 11967, USA
Email marketing_at_creative-biolabs.com
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Creative Biolabs
Thank You
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