VLPs Products in Creative Biostructure

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VLPs Products in Creative Biostructure
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VLP

• Lipoparticles have many advantages in isolating
  membrane proteins firstly, they are homogeneous
  and physically well defined, capable of
  maintaining the native structures of target
  membrane proteins in high densities secondly,
  they can be used to detect membrane protein
  interactions and therefore have wide applications
  in antibody screening, phage and yeast display,
  immunogens production and ligand binding assays.
• Creative Biostructure uses MemPro virus-like
  particles (VLP) to efficiently isolate membrane
  proteins in the form of lipoparticles.

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VLP product

• Creative Biostructure provides VLP products
  containing high concentrations of specific
  membrane proteins in their native conformation.
  VLPs capture conformationally-intact membrane
  proteins directly from the cell surface, enabling
  these complex proteins to be manipulated as
  soluble proteins. Our VLPs are produced with
  specified membrane proteins on a custom basis, or
  are available from a selected catalog of
  ReadyVLPs. Sample kits are also available for
  purchase for preliminary application testing.

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Zika Virus VLP

• Creative Biostructure develops a safe, effective
  and straightforward strategy to rapidly produce a
  Zika vaccine. Our Zika Virus VLPs are composed of
  partially mature particles containing Envelope
  (E), pre-Membrane (prM) and Membrane (M). VLPs
  are produced in mammalian suspension cell
  cultures offering a suitable system for rapid
  scale up of manufacturing, without the risk of
  working with an infectious agent. The lack of
  infectivity of the product eliminates the need
  for chemical inactivation, which may compromise
  vaccine efficacy and safety. The particulate
  nature of the vaccine and the preservation of a
  variety of conformational antigenic sites may
  even render this vaccine efficacious in humans
  without using adjuvant if its incorporation into
  a vaccine raises safety concerns. In summary, the
  Zika VLP platform puts forward a vaccine
  composition and production system ready for
  clinical development of a safe and effective
  prophylactic Zika vaccine, which is greatly
  needed to meet the challenges imposed by the
  spread of the Zika epidemic.

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Contact Creative Biostructure

• Mailing Address 45-1 Ramsey Road Shirley, NY
  11967, USA
• Email Address contact_at_creative-biostructure.com
• Website http//www.creative-biostructure.com