Polycythemia: Causes, symptoms, diagnosis and treatment - PowerPoint PPT Presentation

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Polycythemia: Causes, symptoms, diagnosis and treatment

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Polycythemia is a rare bone marrow disorder, which causes the increase in the production of cells in the blood, mainly red blood cells. The primary function of the red blood cells is to carry oxygen to the different parts of the body. – PowerPoint PPT presentation

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Title: Polycythemia: Causes, symptoms, diagnosis and treatment


1
POLYCYTHEMIA
  • CAUSES SYMPTOMS DIAGNOSIS TREATMENTS

2
WHAT IS POLYCYTHEMIA
  • Polycythemia is a blood disorder in which the
    body produces too many blood cells as a result of
    a problem with the bone marrow or an increased
    production of the hormone erythropoietin (EPO).
  • Polycythemia is defined as an increase in the
    hemoglobin above normal.
  • Often patients with polycythemia are detected
    through an incidental finding of elevated
    hemoglobin or hematocrit levels.
  • Concern that the hemoglobin level may be
    abnormally high is usually triggered at 170 g/L
    for men and 150 g/L for women. Hematrocrit levels
    gt50 in men or gt45 in women may be normal.

3
CAUSES OF POLYCYTHEMIA
  • The most common cause of Polycythemia is genetic.
    The patient of Polycythemia may have inherited a
    gene called, JAK2, the function of this gene is
    to keep the production of red blood cells and
    other blood cells under control.  However, the
    exact cause of Polycythemia is not known. Here
    are some of the common conditions that may
    increase the chance of Polycythemia 

4
CONTINUE- CAUSES OF POLYCYTHEMIA
  • Heart failure 
  • Lack of blood flow in the kidneys 
  • Hypertension 
  • Sleep apnea 
  • Pulmonary disease
  • Placental insufficiency during pregnancy
  • PIH
  • Congenital hypothyroidism
  • Maternal smoking
  • Post date Newborn
  • Maternal diabetes

5
SYMPTOMS OF POLYCYTHEMIA
  • The symptoms of Polycythemia can be easily
    treated if, detected early. No proper treatment
    of Polycythemia in it early stage can lead to
    fatal complications in future. Symptoms of
    early Polycythemia
  • Weakness 
  • Weight loss 
  • Headache 
  • Swelling in joints 
  • Dizziness 
  • Itchiness

6
SYMPTOMS OF POLYCYTHEMIA
  • Symptoms of Polycythemia if left untreated in
    early stage
  • Heart attack
  • Stroke 
  • Deep vein thrombosis 
  • Loss of blood supply to brain 
  • Internal bleeding

7
DIAGNOSIS OF POLYCYTHEMIA
  • The most common method of diagnosing Polycythemia
    is a blood test. A doctor may refer a blood test
    known as CBC (Complete Blood Count).
  • A complete blood test is performed by taking
    blood samples from the patients vein. The
    complete blood test (CBC) evaluates the amount of
    red blood cells, white blood cells and blood
    platelets.
  • Bone marrow biopsy is a procedure in which a
    sample of bone marrow generally taken from the
    back of your hipbone is observed under medical
    supervision.

8
TREATMENTS OF POLYCYTHEMIA
  • Phlebotomy- In this procedure the excess blood in
    the patients body is removed from their vein, to
    make present blood less thick so it can flow
    better. 
  • The specialised treatment of Polycythemia
    involves using, Hydroxyurea and interferon alpha.
    These medicines, suppresses the risk of blood
    clots by reducing the excessive production of red
    blood cells. However, the patients of thyroid
    and mental disorders are, advised not to take
    interferon alpha.

9
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