African Traditional Medicine

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About Sorghum Bicolor Literatures
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ABSTRACT OF SORGHUM LITERATURE

• Trans-piceid and trans-resveratrol were
  authenticated for the first time by
  high-resolution mass spectrometry in red sorghum
  grains

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white sorghum samples

• The white sorghum samples contained only traces
  of trans-piceid (up to 0.1 mg/kg), and
  trans-resveratrol was absent. In much lower
  amounts than procyanidins, stilbenoids are not
  able to contribute significantly to the
  exceptional antioxidant activity

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Growing Interest In Natural Alternatives

• The growing interest in natural alternatives to
  synthetic petroleum-based dyes for food
  applications necessitates looking at
  nontraditional sources of natural colors

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High Performance Liquid Chromatography

• We used High Performance Liquid
  Chromatography-Tandem Mass Spectroscopy to
  characterize sorghum leaf sheath pigments,
  Sorghum bicolor and measured the stability of
  isolated pigments in the presence of bisulfite at
  pH 1.0 to 7.0 over a 4-wk period.

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Anthocyanin Phenolic Contents

• Extracts from leaf sheaths of farmersvarieties of
  dye sorghum cultivated and used in Benin as a
  source of biocoloringswere analyzed for their
  anthocyanidin and phenolic contents, as well as
  their antioxidant capacity.

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The Apigenin Content Of Theleaf Sheaths

• The apigeninidin content of theleaf sheaths was
  30 times higher than that in cereal bran and
  ranged from 14.7 to 45.8 mg/g, with an average of
  31.3 mg/g.

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Opportunities For Food Applications.

• It increased molecular complexity of the dimeric
  3-deoxyanthocyanidins compared to their monomers
  may be responsible for their unusual stability in
  the presence of bisulfite these compounds
  present new interesting opportunities for food
  applications.

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Chemical Biochemical Properties

• 3-Deoxyanthoxyanins (3-DXA) possess unique
  chemical and biochemical properties and may be
  useful in helping reduce incidence of
  gastrointestinal cancer

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Health-Promoting Phytochemicals.

• 3-Deoxyanthocyanidins are structurally related to
  the anthocyanin pigments, which are popular as
  health-promoting phytochemicals. Here, it is
  demonstrated that the 3-deoxyanthocyanidins are
  more cytotoxic on human cancer cells than the
  3-hydroxylated anthocyanidin analogues and
  natural remedy for diabetes

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Highly Virulent Diseases

• Cancer is one of the highly virulent diseases
  known to humankind with a high mortality rate.
  Breast cancer isthe most common cancer in women
  worldwide. Sorghum is a principal cereal food in
  many parts of the world, and is critical in folk
  medicine of Asia and Africa.

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Natural Cancer Therapy

• Usage of HS as a dietary supplement is an
  inexpensive natural cancer therapy, without any
  side effects. We strongly recommend the use of HS
  as an edible therapeutic agent as it possesses
  tumor suppression, migration inhibition, and
  anti-metastatic effects on breast cancer

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vascular endothelial growth factor (VEGF)

• PARE administration inhibited tumor growth and
  metastasis formation by suppressing vascular
  endothelial growth factor (VEGF) production. The
  results suggested that PARE had antioxidant and
  antitumor activities.

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