Generic Morphine Sulphate 50mg Vial

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Generic Morphine Sulphate 50mg / Vial
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• Generic Morphine Sulphate MAGNUS MR 30mg/2ml /
  Amps Therapeutic ClassNarcotic analgesic
  CompositionMagnus MR 2ml vial containing
  morphine sulphate 30 mg/2mlDescriptionMorphine
  applies an agonist effect at saturable opioid
  receptors in the CNS and other tissues acts as
  opioid analgesic.

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• Morphine is an analgesic drug used to treat acute
  and chronic pain. Obesity is frequently
  associated with pain of various origins (e.g.
  arthritis, fibromyalgia, cancer), which increases
  the need for analgesic drugs. Obesity changes
  drug pharmacokinetics, and for certain drugs,
  specific modalities of prescription have been
  proposed for obese patients.

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• However, scant data are available regarding the
  pharmacokinetics and pharmacodynamics of morphine
  in obesity. Prescription of morphine depends on
  pain relief but the occurrence of respiratory
  adverse effects correlates with obesity, and is
  not currently taken into account.

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• Variations in the volume of distribution,
  elimination half-life and oral clearance of
  morphine, as well as recent advances in the
  respective roles of drug-metabolizing enzymes,
  catechol-O-methyltransferase and the µ opioid
  receptor in morphine pharmacokinetics and
  pharmacodynamics, may contribute to differences
  between obese and non-obese patients.

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• In addition, drug-drug interactions may alter the
  disposition of morphine and its glucuronide
  metabolites, which may either increase the risk
  of adverse effects or reduce drug
  efficacy.Indications

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• Severe chronic pain or pain resistant to other
  analgesics, in particular pain associated with
  cancer.DosageAdultsRecommended dosage is one
  injection daily. ElderlyAs with all narcotics a
  reduction in dosage may be advisable in the
  elderly, as appropriat

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