Aptamers Market - Technology Trend

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Aptamers Market - Technology Trend
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Summary
Aptamers is an emerging market, widely considered
as a rival or substitute to antibodies in the
scientific industry. It is poised to grow rapidly
in various application areas, including
therapeutics and diagnostics. The global aptamers
market is valued at 287 million in 2013 and is
expected to reach 2.1 billion by 2018. Aptamers
existed in parallel with antibodies for two
decades, but its market potential was not
utilized, even to a fraction of antibodies.
However, the achievement of Macugen has given a
boost to the aptamer field. The list of promising
aptamers in the clinical trials pipeline
estimates that these synthetic chemical
antibodies will soon surpass monoclonal
antibodies in therapeutics, diagnosis, and
imaging. With technological merits over
antibodies, the aptamers market is poised to grow
at par with antibodies in the next 10-15 years.
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Though there are just lt 60 companies (biotech and
pharmaceutical) working on aptamers, there are
quite a number of research groups working on
diverse applications of aptamers, particularly in
studying key target molecules involved in
cardiovascular diseases, infectious diseases, and
against viral antigens. Hundreds of research
articles have been published and a lot of patents
granted and filed for this technology. The
aptamers market is analyzed both in terms of
qualitative, i.e. technological and quantitative,
i.e. revenue, perspectives. The technological
analysis includes discussion on inherent
characteristics and capabilities of aptamers over
antibodies and the various applications where
aptamers can find its place. The market revenue
analysis includes market segmentation and the
expected market position by 2018, with the
projected growth rate.
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The aptamers market is classified by geography,
application segments and aptamer type. The
application segments are further divided as
therapeutics, diagnostics, biosensors, drug
discovery, biomarker discovery, and research
applications. The advantages of chemically
modified aptamers and low production cost
compared to antibodies aid the growth of the
market. However, the reduced market acceptance
compared to the antibodies and increased time
consumption for screening using SELEX will hamper
the growth of this market, to a certain extent.
While aptamer technology has existed for over two
decades, the challenges imposed on the
development of aptamers for small molecules has
resulted in very few novel aptamers that can bind
to practical small molecular targets.
Nevertheless, there are many opportunities for
the innovative application of small molecule
binding aptamers in biosensing, drug discovery,
diagnostics and therapeutics.
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Besides a discussion on the properties of
aptamers in the technological analysis, the
basics on nucleic acid aptamers, peptide aptamers
and the SELEX method for their synthesis are also
discussed. In addition, a number of therapeutic
targets that are validated by basic research have
been displayed under the therapeutics application
segment. The complete value chain of the aptamers
market is schematically represented and the
significance of each stakeholder has been
briefed. Apart from the technological and market
analysis, the investor climate has been assessed
by tracking the complete investor network and
collecting data on funds/grants and investments
made towards the aptamers. Insights on current
and future technological investment trends have
also been discussed.
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Table Of Content

• Introduction
• Executive Summary
• Aptamers Technology Landscape Analysis 
• Aptamers Market Landscape Analysis
• Technology Investment Potential 
• Aptamers Technology Adoption And Development
  Potential 
•  Aptamers Competitive Landscape 
• Intellectual Property And Research Strength
  Analysis
• Analyst Insights And Recommendations
• Company Profiles

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