Human Genome Project

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Human Genome Project

• Long completed began 60 years ago
• Goal is to understand control
• Supercomputers are key
• Bioinforamtics
• Information science
• Biology
• Medicine
• Genome mapping
• Drug DNA matching
• Predictive-preventive

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Genotyping

• Still controversial your DNA tells all
• Genotyped people get best care
• Single nucleotide polymorphisms (SNP)
• 0.1 of total DNA
• Only 20 main SNP classes
• determines you and health characteristics.
• SNP uses
• Easier diagnosis predicable problems
• Better preventative medicine
• Customized medicine by SNP class

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Genotyping cont.
The haplotypes in the human genome have been
produced by the mechanisms of reproduction and
record the history of our species.
They are closely linked genetic markers in a
chromosome inherited as a group
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Bioinforamtics

• DNA decoded Blue Gene unlocked code
• 2005 180 days to decode the 3.2 billion DNA
  letters
• 2055 decode/profile in 8 minutes and affordable
• Today, diagnose, predict, fix/modify as required

BioMEMS analyzer
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Important Bio-med Areas

• Monitors - Implanted data via wireless.
• Pharmacy-on-Chip provides medication
• Gene modification
• Nano-robotics for body maintenance and repair

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Simple Bio Implants
wireless
Wireless Personal monitoring
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Cosmetic Surgery

• Popular
• Standard library
• Computerized
• Mostly robotic (CAD-like)

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Early Bio Detector
500 µm long, 100 µm wide and about 1 µm thick
IBM
Pathogen/Bad Gene Detector
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Lab-on-Chip
DNA can be amplified, separated and identified on
a chip
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Lab on Chip Diagram
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Portable DNA Examples

Caliper Tech.
NanoChip Electronic Microarray
pumping occurs by applying electric voltage to
fluid.
Sandia
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Sight Restoration 2015
Or link directly to
iHUD
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FluidFocus Lens
Phillips
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Sight Restoration 2055

• Retina regeneration
• Optic nerve repair
• Replacement optics
• Grown and transplanted bio-parts
• Moving toward eye grown in place

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Fantastic Journey?

• Turbines
• Tweezers
• Cutters
• Detectors
• Sensors
• Pumps
• Legs
• Wireless
• Jets
• More

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Death

• Intervention up to age 80
• Euthanasia acceptable, but not suicide
• You may be reactivated in suicide for obligations
• Immortality research was banned in 2025
• Near-mortality is feasible neg. consequences

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Birth in the Brave New World

• Parents/Donors DNA QCd
• Gene adjustment OK
• No super babies allowed
• Minor modification gene defect repair
• Gene libraries limited use
• Will birth parents matter?