CONSTITUTIONAL SYMPTOMS

1
CONSTITUTIONAL SYMPTOMS

• Reassurance
• Rest/exercise
• NSAID
• Antimalarials
• Steroids (e.g. Prednisone lt .25 mg/kg/day)
• DHEA
• TCA/SSRI/Behavioral or cognitive therapy

2
CUTANEOUS

• Sun avoidance/sunblock
• Steroids (topical and intralesional)
• Hydroxychloroquine (plaquenil)
• Chloroquine (aralen)
• Quinacrine (atabrine)
• Dapsone
• Retinoids (isotretinoin)
• Clofazamine
• Azathioprine

3
ARTICULAR

• NSAID
• Antimalarials (HCQ, CQ)
• Methotrexate
• Azathioprine
• Steroids (e.g. Prednisone lt .25 mg/kg/day)

4
HEMATOLOGIC (AIHA/AITP)

• Steroids (e.g. Prednisone 1 mg/kg/day
  
• Decadron 40 mg day x 4 days)
• Danazol
• Dapsone
• Vincristine
• Cyclophosphamide
• Intravenous immunoglobulin (IVIG)
• Splenectomy
• CSF (Epogen, Neupogen)

5
SEROSITIS

• NSAID (e.g. Indomethacin)
• Antimalarials (HCQ, CQ)
• Steroids (e.g. Prednisone lt .5 mg/kg/day)
• Aspiration

6
VASCULITIS

• Steroids (e.g. Prednisone 1 mg/kg/day)
• Cyclophosphamide
• Plasmapherisis (especially TTP/TMHA)
• Intravenous immunoglobulin (IVIG)

7
Current Management of Lupus Glomerulonephritis

• Steroids oral daily or QOD
• Pulse solumedrol
• Cyclophosphamide
• Azathioprine
• Cyclosporine
• Methotrexate
• Plasmapheresis ? synchronized
• Intravenous gammaglobulin
• Mycophenolate mofetil
• 2 chlorodeoxyadenosine
• Fludarabine
• Recombinant human DNAse
• NSAID
• ACE inhibitors
• Low protein diet

8
NERVOUS SYSTEM

• Steroids (e.g. Prednisone 1 mg/kg/day)
• Cyclophosphamide
• IVIG
• Psychotropics (e.g. Haloperidol)
• TCA/SSRI