Generic Propecia treats Male Pattern Baldness

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Generic Propecia treats Male Pattern Baldness

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Title: Generic Propecia treats Male Pattern Baldness


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Generic Propecia treats Male Pattern Baldness
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Generic Propecia Information
  • Generic Propecia (generic name Finasteride) is a
    drug used for the treatment of male pattern
    baldness and, under the Proscar brand, enlarged
    prostates.
  • Generic Propecia is produced by the
    pharmaceutical company Merck. It is the biggest
    brand for the drug named finasteride but there
    are other generic brand names for this compound.
    You can buy generic propecia online from online
    pharmacy.

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How does Generic Propecia work to treat male
pattern baldness?
  • Generic Propecia main ingredient is a chemical
    that inhibits the enzyme type II 5a-reductase.
    This enzyme converts the male sex hormone
    testosterone into dihydrodeoxycorticosterone
    (DHT). Male pattern baldness occurs when there is
    too much DHT in the scalp. Normal hair production
    and maintenance processes are disrupted, and the
    scalp slows down hair production or, in many
    cases, stops production altogether. The culprit,
    in this process, is DHT. Finasteride (Propecia)
    helps increase the scalp's hair levels or reduces
    hair loss by actively blocking the production of
    DHT.

5
Generic Propecia Effectiveness
  • Generic Propecia looks to be a really effective
    drug if you consider the remarkable difference
    between the results experienced by the control
    group compared to the ones experienced by the
    test group.
  • According to studies, Finasteride is only
    effective as long as the patient continues to
    take it. If you decide to stop using Generic
    Propecia, you may again experience hair loss
    after about six months to a year. Unfortunately,
    you will also lose the hair that you have gained
    during the active treatment period, and hair loss
    is again reactivated.If you do make use of
    Generic Propecia, you will experience that it is
    most effective on particular parts of your scalp.
    You will find the best hair growth on the crown
    of your head, though the medication is really
    designed to restore hair and stop hair loss not
    only at the crown areas, but also at the
    hairline.

6
How does Finasteride block DHT production?
  • The male sex hormone testosterone is produced
    mostly in the male's testes and adrenal glands.
    Testosterone binds to a liver-produced protein
    called SHBG (sex hormone-binding globulin). By
    preventing testosterone from being metabolized by
    the body, SHBG enables testosterone to be
    transported to the body's cells. In certain parts
    of the male body, primarily the prostate, skin,
    and scalp, testosterone is turned into a more
    potent form called 5a-dihydrotestosterone (DHT).
    This conversion is made possible by 5a-reductase,
    an enzyme. DHT is an amplified and more powerful
    version of testosterone since it has triple to
    ten times the potency of testosterone as measured
    by androgen reception. DHT is made in the
    following areas of the body prostate, hair
    follicles, skin, and testicles. DHT is easier to
    absorb that testosterone. In short, 5a-reductase
    is crucial to boosting the male body's DHT
    levels. DHT causes baldness because hair
    follicles are very sensitive to DHT. Hair
    follicles respond to elevated DHT levels by
    shrinking. As a result, they produce less and
    less hair or thinner hair. Given sustained and
    prolonged high levels of DHT, hair follicles stop
    producing hair. Similarly, high levels of DHT in
    the prostate can lead to prostate enlargement.
  • Finasteride binds with 5a-reductase so it doesn't
    convert as much testosterone into DHT.Since
    Finasteride effectively 'mops up' 5a-reductase so
    there are less of this enzyme in the blood
    stream, the body's overall levels of DHT drops.
    Lower DHT levels in the scalp and prostate
    reduces or even eliminates these tissues'
    reactions to elevated DHT levels. As mentioned
    above, the scalp's reaction to DHT is to shrink
    follicles. The prostate, on the other hand,
    expands due to increased DHT.
  • By keeping DHT levels in check, Finasteride
    enables regular follicle growth and keeps the
    prostate from enlarging.

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How was finasteride discovered?
  • In the mid-70s, a conference presentation by
    Cornell's Julianne Imperato-McGinley showed a
    link between lower levels of DHT and 5a-reductase
    and smaller prostates and the absence of male
    pattern baldness. Merck's head of research read
    the presentation notes and went to work on
    developing a compound that can lower DHT and
    5a-reductase in order to treat enlarged
    prostates. The resulting drug, Finasteride,
    gained FDA approval for benign prostatic
    hyperplasia in 1992 and male pattern baldness in
    1997.
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