Research Facilities

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Research Facilities Resources
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Overview

• Community-based research clinic in San
• Gabriel valley
• Well-developed infrastructure and facilities
• DOM resource administered by Division of
• Geriatrics
• Growing links with other DOM and SOM core
  research resources

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134
Altadena
210
Pasadena
Eagle Rock
Arcadia
San Marino
South Pasadena
Highland Park
San Gabriel
Temple City
RCA
110
Rosemead
LA County-USC Hosp
10
Monterey Park
UCLA
South El Monte
710
Boyle Heights
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Facilities

• Clinic space 2 suites of exam/procedure rooms
• Large 8 pt rooms Small 6 pt rooms
• Each has scales, stadiometers, sphygs, phlebotomy
  station, locker room
  
• Snack room
• Kitchen for food storage

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Facilities

• Specialized technologies
• Ultrasound
• ECG
• Fundus photography
• DEXA (Hologic 4500)
• Secure medication storage
• Regular inventory
• Experienced with automatic phone dispensing

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Facilities

• Laboratory
• Refrigerated centrifuge
• -20C and 80C storage freezers (limited)
• CLIA certified

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Facilities

• Educational
• Flexibly configured classrooms
• Grouped workstations for 6 participants
• Audiovisual equipment
• Telephone / in-person surveying
• 6-line phone bank available
• Community-based data collection
• Headquarter staff with easier access to community
  sites such as schools and senior centers
  
• Offices linked to UCLA infrastructure

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Staff Resources

• Experienced study coordinators, data collectors,
  and recruiters
  
• Many staff bilingual (Spanish, Mandarin,
  Cantonese, Vietnamese, Farsi)
  
• Certified phlebotomists, medical assistants,
  laboratory assistants DEXA technicians

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Staff Resources

• Data processing and management
• Regulatory and fund management
• Nutritionists
• Specialized software development (Available
  through OAIC-ROC)
  

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Accessibility

• 2 passenger vans staff drivers for transporting
  participants
  
• Free parking
• Handicap access
• Convenient public transportation

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Research Support Services

• Initial evaluation meeting
• Feasibility for RCA, resource needs/availability,
  costs
  
• Proposal preparation
• Operations budget justification, boilerplate
  text
  
• Project implementation
• Staffing, training, certification
• Coordination with other RCA projects (staff,
  space, transportation, other resources/equipment)
  
• IRB correspondence

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Linkages

• Westwood GCRC/proposed CTSI
• Office of Clinical Trials
• UCLA Older Adults Independence Center
• 4 research cores Research Operations,
  Recruitment, Analysis/Cost-Effectiveness,
  Inflammatory Biology
  
• In development
• Resource Center for Minority Aging Research
• UCLA-Harbor GCRC

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Data Management Expertise

• Through OAIC Research Operations Core
• Help with quality control flow
• Development of protocols manuals
• Design training and certification sessions
• Data flow and review analysis
• Data entry application and design
• Analysis of data forms for collection entry
• Pepper Informatics

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Current Studies

• Multi-Ethnic Study of Atherosclerosis (MESA) (PI
  Karol Watson) affiliated ancillary studies
  
• Longitudinal study of 4 ethnic groups
• Observational study started in 2001
• Physical exam, interviews, imaging, phlebotomy
• Ancillary studies consist of similar exams
• MESA Air (PIAdrian Casillas)
• Original MESA cohort plus new Riverside Santa
  Monica residents, 2006-2007
  
• Exam similar to MESA, adding air quality
  monitoring

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Current Studies

• Diabetes Prevention Project Outcome Study
  (DPPOS) (PI Karol Watson)
  
• Originally randomized trial for diabetes
  prevention through metformin or lifestyle
  intervention
  
• Physical exam, interviews, phlebotomy
• Behavior interventions and health education
• Diabetes education programs (PI Preethi
  Srikanthan)
  
• Two small pilots examining feasability of
  computer-based education modules to
  Mexican-Americans

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Current Studies

• Pharmaceutical trials (PIs Karol Watson
  Christine Darwin)
  
• Trials for a variety of sponsors (Novartis, Novo
  Nordisc) targeting outcomes related to diabetes
  or cardiovascular health
  
• Dispense medication conduct physical exams as
  indicated by protocol
  

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Costs

• Costs competitive with on-campus costs
• On campus 54 IDC off campus facility fees
  26 IDC
  
• Direct personnel costs are fee for service (e.g.,
  interviewers, phlebotomists)
  
• Small projects may have facility fees waived

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Summary

• Location
• Access to diversity of ethnic communities
• Facilities
• Clinic classroom space, phlebotomy, lab w/
  temporary specimen storage, ultrasound, DEXA,
  ECG
  
• Staff
• Experienced multi-lingual project directors and
  research staff, data management staff and software

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For further information, contact Heather
McCreath, PhD
330 S. Garfield, Suite 308Alhambra, CA
91801(626) 979-4920

• [phone]
• e-mail hmccreath_at_mednet.ucla.edu