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ACUTE PASSIVE HYPEREMIA/CONGESTION, LUNG

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This is one of the most common special stains performed in the pathology lab, ... Liver all those red ... and is associated with necrosis in the CENTRAL part of the ... – PowerPoint PPT presentation

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Title: ACUTE PASSIVE HYPEREMIA/CONGESTION, LUNG


1
ACUTE PASSIVE HYPEREMIA/CONGESTION, LUNG
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PRECEDES ACUTE PULMONARY EDEMA
2
  • Heart failure cells are hemosiderin laden
    macrophages. Blood escapes into the alveolar
    space because chronic congestion causes the thin
    walled alveolar capillaries to burst..
  • Note the thickening of the alveolar septae. This
    is caused by chronic pulmonary congestion and
    edema.

3
CHRONIC PASSIVE HYPEREMIA/CONGESTION, LUNG
PRUSSIAN BLUE stain is a fairly specific BLUE
stain for hemosiderin pigment. This is one of the
most common special stains performed in the
pathology lab, along with the trichrome stain,
which is a fairly specific stain to stain
collagen GREEN!
4
Acute Passive Congestion, Liver
all those red dots are congested central veins!
5
Acute Passive Congestion, Liver
the central vein and sinusoids are distended with
blood, and there may even be central hepatocyte
degeneration the periportal hepatocytes, better
oxygenated because of their proximity to hepatic
arterioles, experience less severe hypoxia and
may only develop fatty change
6
CHRONIC PASSIVE HYPEREMIA/CONGESTION, LIVER
NUTMEG liver is associated with necrosis in the
CENTRAL part of the hepatic lobule. This can
progress to cirrohsis, and therefore if the
congestion is cardiac in origin, the type of
cirrhosis is called CARDIAC cirrhosis. The term
centrilobular necrosis usually goes hand in hand
with the word chronic passive congestion.
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a saddle embolism
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WEDGE SHAPED SCARRED INFARCT following the
distribution of a end artery branch of the renal
artery. FIBROSIS implies that it is old (months
to years)
10
ATHEROSCLEROTIC PLAQUE
NORMAL ARTERY
ATHEROSCLEROTIC PLAQUE
11
Thrombus Causing MI
needle-like white spots are cholesterol crystals
12
Atherosclerotic Plaque Histology
cholesterol crystal (cleft)
foam cells
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