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MALARIA

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MALARIA PLASMODIUM VIVAX PLASMODIUM FALCIPARUM PLASMODIUM OVALE PLASMODIUM MALARIAE Dr.Rita Swaminathan Mr.Narayana Kamath LIFE CYCLE ALTERATION OF GENERATIONS ... – PowerPoint PPT presentation

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Title: MALARIA


1
MALARIA
  • PLASMODIUM VIVAX
  • PLASMODIUM FALCIPARUM
  • PLASMODIUM OVALE
  • PLASMODIUM MALARIAE
  • Dr.Rita Swaminathan
  • Mr.Narayana Kamath

2
LIFE CYCLE
  • ALTERATION OF GENERATIONS
  • asexual cycle (schizogony)
  • sexual cycle (sporogony)
  • ALTERATION OF HOSTS
  • intermediate host (man) schizogony
  • definitive host (mosquito) sporogony

3
Life cycle
4
Morphology-thin blood smear
 
nucleus
ring
cytoplasm
5
Morphology-thick blood smear
ring
6
Morphology
Male gametocyte
Female gametocyte
7
Pathogenesis and Clinical features
  • Pre-patent period, incubation period
  • Febrile paroxysms(Erythrocytic schizogony)
  • Hot stage , cold stage sweating stage
  • Anaemia
  • Splenomegaly
  • Complications of P.falciparum

8
Laboratory diagnosis
  • Peripheral smear
  • Thick smear,Thin smear
  • CBC
  • Flourescent microscopy(QBC)
  • Rapid tests Malaria Ag detection test
  • DNA probes
  • Seroloical tests(ELISA)

9
Treatment prevention
  • Chemotherypy Antimalarial agents
  • Antimosquito measures
  • Early diagnosis and radical cure for relapses
  • Malarial vaccine
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