Futures in Biotechnology

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Futures in Biotechnology

• Kirk Brown
• Tracy High School

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Science Fiction to Science Fact

• Congenital Generalized Hypertrichosis (CGH)
• Xq24-q27.1

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Technology is Rapidly Changing

• What was once science fiction is now science fact.

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What is Biotechnology?

• New technology related to living things
• Producing a product from one organism in another.

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Students Extracting DNA
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Human Genome Project

• Progress Toward HGP Sequencing GoalsWorking
  draft sequenceGoal 100 by summer
  2000Finished, high quality sequence Goal 100
  by 200318.2 (586,045,000 bases) (04/15/00)

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Chromosomal Technology

• Karyotype
• Simple stain
• Done by Hand
• Pictures cut out and pasted on a piece of paper.

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Chromosomal Technology

• Chromosomal Painting
• Can show changes in chromosome structure.

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Chromosomal Technology

• Spectral Karyotyping
• Each Chromosome can have its own color.
• In the near future each gene can have its own
  color.

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New Genetic Testing Technology

• Affymetrix
• DNA Chip
• Hundreds of Tests at a time.
• The results are scanned by a laser and fed into a
  computer.

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The Future Needs a Skilled Workforce.

• Computers to Help in Analyzing Large Sets of
  Data.
• A workforce that can understand what is being
  tested.

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Computers as tools

• All the information that is being gathered must
  be cataloged and entered before it can accessed
  by researchers.

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Automated Analysis

• Once a DNA sample is prepared it can be compared
  to all other samples in the database.

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Computer Analysis

• Confirming the Romanov Familys mtDNA sequence.

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New Discoveries Bring More Choices

• As progress is made in biotechnology, people have
  more information regarding themselves.
• Are they ready for the choices?

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Imaging Technology

• PET Scan
• Computers and machines are directly linked.
• MRI or Magnetic Resonance Imaging also relies on
  computers.

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Analysis and Production of Standards.
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New Procedures Lead to New Technology

• New Sequencing Technology has driven the need for
  a skilled workforce.

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Everyone Should Understand the Issues Generated
by Biotechnology
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Impacts to Education

• All areas of the curriculum are impacted.
• Students become teachers in some cases.

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THS Student Laboratory Work

• Inserting a gene from one organism into another.
• DNA fingerprinting to identify different
  bacterial plasmids.
• Fish Fingerprinting to determine relationships.

• Enzyme studies to determine cost effective
  methods of making sugar.
• Analyzing areas of our own chromosomes by PCR.
• Etc

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Discoveries Happen in the weirdest places!

• Deep in the ocean is were organisms dont rely on
  light or other organic sources.

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Questions?