Optical Coherence Tomography (OTC) David Berman A Brief

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Optical Coherence Tomography(OTC)
David Berman
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A Brief History of OTC

• Devised in 1990 by Naohiro Tanno
• 1991 30µm resolution
• 2001 sub micron resolution
• (wide bandwidth light sources with ? at 100nm
  range)
• Been used to analyze different layers of paintings

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How It Works

• A-scan Reflectivity Profile
• B-scan Series of A-scans to provide 3D

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The Math Behind OTC
Interference (beam splitting/intensity)
Complex Degree of Coherence (time delay)
Doppler Shift
Coherence Length
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Features/Advantages

• Live sub-surface images at near-microscopic
  resolution
• Enables instant, direct imaging of tissue
  morphology
• No preparation of the sample or subject is
  required
• No ionizing radiation enabling safe use in
  office, laboratory or clinic
• 2-3 mm penetration in tissue
• Based on optics rather than radio waves

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Equipment
MelaFindTM Probe (Courtesy Electro-Optical
Sciences, Inc. NY)

• Courtesy University of Miami OCT Clinic)

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Ophthalmology
Age-related macular degeneration
Normal retina (fovea)
Macular hole
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Dermatology
3D Image of Thumb

• (Courtesy University of Miami OCT Clinic)

TS2000M (Courtesy TransScan Medical Ltd., Migdal
HaEmek, Israel)
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References

• http//homepage.mac.com/omca/somca/nog/oct.html
• http//webeye.ophth.uiowa.edu/dept/IAEyeNws/IAeye0
  4/OCT.htm
• http//www.revophth.com/index.asp?page1_860.htm
• http//lob.epfl.ch/page46528.html
• http//www.ne.anl.gov/capabilities/sinde/highlight
  s/work_for_others.html
• http//en.wikipedia.org/wiki/Optical_coherence_tom
  ography