Group 5 Developing Diagnostic Guidelines

1
Group 5 Developing Diagnostic Guidelines

• China, Hungary, Spain, Sweden, Austria, USA,
  Israel, South Africa

2

• Disease/condition driven
• For diagnosis, monitoring and/or screening
• Include preanalytical concerns
• Include algorithms, as appropriate
• Consider the environment in which the guideline
  will be used
• Global
• Regional
• Local

3

• Identify target population
• Who will use the guideline
• Who will gain from the guideline
• Guideline Development Group
• Multidisciplinary laboratorians, clinicians,
  nurses, etc.
• Include professional and clinical associations
• How will the group be funded

4

• Assess the impact of the guideline
• Impact on clinical decisions/monitoring patients
• Shortcomings/limitations
• How will the guideline be disseminated
• National guideline clearing houses
• When does the guideline need to be updated
• Quality of the guideline
• Evidence-based when possible
• Identify limitations (e.g. not studied in all
  ethnic groups)

5
Potential topics for Guideline Development

• Infectious Diseases
• Hepatitis HIV
• Prenatal Screening
• Screening for Downs Syndrome
• Fertility Screening
• Inborn errors of metabolism
• Heterogeneity of the population sequence of
  testing
• Iron Status
• Iron overload, anemia