Should Truvada Be the FirstLine Regimen Presentations and Discussion

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Should Truvada Be the First-Line
Regimen?Presentations and Discussion

• Jon Kaplan
• Anthony Amoroso
• Barb Marston
• Jeff Stringer
• Phyllis Kanki

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Why an issue now?

• Kigali HIV Implementers Meeting
• Zambia MOH made TDF/FTC first line NRTI
  backbone in June 2007
• Cost of TDF (vs. current regimens) will challenge
  attainment of treatment goals
• In COP 08 will more countries be requesting
  funding for TDF regimens?

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First-line ARV drug regimens, June 200623
countries with 786,000 patients on first line
ART (not including SA, Brazil, Botswana)
From Renaud-Théry et al, AIDS 2007 21S89-S95
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Measuring Progress in Treatment 07 SAPR Data
550,000
1000,000
Mozambique