Medical Imaging and How to Catch a Beating Hear

1
Medical Imaging and How to Catch a Beating Heart?

• Dr. Nael Osman
• Nile University
• Johns Hopkins University

2
Mission

• To establish a world class center for Medical and
  Health Informatics, especially in Medical Imaging
  technologies, and pursue strong collaboration
  with local, regional, and international entities.

3
Example Heart

• Its the number one killer!
• Very expensive The US alone spends over 450
  billion a year.

4
Challenges to Imaging the Heart

• Soft tissue
• Hiding inside the chest cage, behind the ribs
• The heart beats at a rate of 70 beats per minute
• The breathing causes another motion challenge

5
(No Transcript)
6
Magnetic Resonance Imaging (MRI)

• Magnetic Resonance Imaging (MRI) images the
  magnetization of the body tissue (water protons)
  when exposed to strong magnet.

7
Gating for Image Acquisition

• It takes 500 ms to make an image.
• We have only 30 ms window for acquisition.
• Solution Gating!

8
Heart Movies
9
Imaging More Than Just Anatomy
10
Combining LT and HT images
strain
LT
SENC
HT
anatomical
11
Patient with Heart Infarction

• Direct imaging of strain (through-plane strain).
• No need for sophisticated post processing.

Red coloring indicates regional shortening strain
in the through-plane direction
12
(No Transcript)
13
1.1) Obtain Anatomical image by superposition of
LT and HT.
Strain Computation
Superposition
Blue coloring
1.2) Compute Strain values from LT and HT.
1.3) Generating a blue color from NT.
14
The anatomical images can be combined with strain
and contrast images to produce
15
The anatomical images can be combined with strain
and contrast images to produce
Functional (contractility),
Viability, or
Composite images.
16
Tissue Characterization Using Clustering Methods
17
In Summary Integrated Analysis
18
Se, we do not see images only
19
but have a comprehensive analysis, too.
20
Acknowledgments

• Students/Ex-students
• Li Pan
• Ahmed Fahmy
• El-Sayed Ibrahim
• Tamer Basha
• Ahmed El-Harouni
• Monda Shehata
• Yue Li
• Ayman Khalifah
• Collaborators (JHU)
• Matthias Stuber
• Robert G. Weiss
• Dara Kraitchman
• Joao A. C. Lima
• David A. Bluemke
• Shenghan Lai
• Katherine Wu
• Michael Schär
• Albert Lardo

• Collaboratores
• Eike Nagel
• Henning Steen
• Thomas Thouet
• Dirk Lossnitzer
• Ahmed Gharib
• Sponsors
• NHLBI Grant HL072704
• Donald W. Reynolds Foundation
• Diagnosoft, Inc.

21
Thank you!
22
(No Transcript)