Confabulation and Frontotemporal Dementia

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Confabulation and Frontotemporal Dementia

• Nathan Spreng
• Rotman Research Institute
• University of Toronto
• 7 July 2004, Xylocastro

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Case Study J.S.

• Male
• Born 1938
• Married, no children
• Occupation Vice president of a major Canadian
  supermarket chain
• Tested Feb 2002, Oct 2003

(McKinnon, Spreng Levine, in preparation)
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J.S.

• Referred to neurologist Oct 2001
• Disinhibitted and socially innapropriate
  behaviour
• Diagnosis Frontotemporal Dementia
• Neuropsychological Examination Feb 2002
• lying

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J.S.

• MMSE 26
• Memory
• Language
• Executive Functioning
• Psychosocial Outcome

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J.S. Frontotemporal dementia
R
R
L
L
R
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J.S.

• Between Feb 2002 and Oct 2003
• Confabulation
• Cued
• Spontaneous
• Dalla Barba Confabulation Battery

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Detroit

• MK Can you tell me about Detroit again?
• JS We were in this nice restaurant and a guy
  said I dont think you guys should go outside.
  Theres a sniper on the roof outside. He said I
  think you had better stay in here. Ive just
  called the cops. (laughter) He said theres a
  sniper on the roof. He said you guys had better
  stay in here.
• MK Then what happened?
• JS Well the cops came. The cops got the guy.
  And they said okay guys you can leave now. That
  was all the help and we went outside.

8
J.S.

• Re-Scanned MRI
• SABRE (Semi-Automated Brain Region Extraction)
• DLPFC

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(No Transcript)
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New Orleans 1

• MK Did you ever visit New Orleans?
• JS Oh yeah, Ive been to New Orleans a lot.
• MK What happened there?
• JS Oh, we had an operation in New Orleans.
• MK Do you remember anything that happened in
  particular in New Orleans?
• JS Yeah when I was there (laughter) I pulled the
  guys paper out and a magnum fell on the floor
• MK A Magnum?
• JS Yeah, a gun. I looked at the gun. He said,
  I always carry a gun in the car. You always
  carry a gun in the car? He said, I always
  carry a gun in the car

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New Orleans 2

• JS I was staying in a very fancy hotel in New
  Orleans and I walked around the corner one day
  and the cops were beating up a guy. (laughter)
  And the cops looked at me and they all said Oh!
  They left the guy and the guy came over and
  said, Thanks a lot sir.
• MK What happened next?
• JS Nothing. He said Thanks a lot. Im really
  glad you came out. He said, The cops are
  really bad here. He said, I owe some of those
  guys money.
• MK What happened after that?
• JJS Nothing. He just said, Come on, Ill take
  you to some really good bars in New Orleans.