Unknown

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Unknown 113
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• A 60 y/o male with known history of
  hemochromatosis presents with acute swelling,
  erythema, and pain of the right big toe.
  Aspirate of the joint reveals a crystal
  arthropathy.

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• 1. Name the type of crystal that would likely be
  found in this acute arthropathy.
• 2. Name 2 other causes for this type of
  arthropathy

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Answers
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Calcium Pyrophosphate Dihydrate Deposition Disease

• Acute or recurrent monoarticular inflammatory
  athropathy that mimics gout
• Positive birefringent rhomboid-shaped crystals
• Onset after age 60
• Suspect in any patient that presents with
  accelerated or unusual distribution of DJD

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(No Transcript)
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Associated conditions

• Hemochromatosis
• hypophosphatemia
• Thyroid (hypothyroid)
• Parathyroid (hyperparathyroid)
• Gittelmans syndrome
• Gout
• X-linked hypophosphatemic rickets
• Familial hypocalciuric hypercalcemia
• Hemosiderosis
• Trauma
• Joint injections

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Clinical Manifestations

• Asymptomatic or incidental finding
• Recurrent acute inflammatory monoarticular
  arthritis
• acute hemarthrosis
• Chronic degenerative arthritis
• Chronic symmetric inflammatory polyarthritis
• Systemic illness ("pseudopolymyalgia rheumatica,"
  fever of unknown origin)
• Carpal tunnel syndrome

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Chondrocalcinosis