Title: Water and Minerals: The Ocean Within
1Water and Minerals The Ocean Within
Chapter 8
2Water and Minerals
- Minerals
- Naturally occurring
- Inorganic
- Homogenous
- Chemical elements
- Major minerals
- Essential nutrients
- Found in the body in amounts exceeding 5 grams
- Trace minerals
- Essential nutrients
- Found in the body in amounts less than 5 grams
- With death all that we leave behind is about 5
pounds of minerals
3Water
- The body needs more water per day than any other
nutrient
- You survive a deficiency of any other nutrient
for months or years
- You only survive a few days without water
- In less than a day, a lack of water alters the
bodys chemistry and metabolism
- Water makes up 60 of an adults body weight
- Water is found in--Blood vessels, cells, chemical
structure of cells, tissues, organs
- Water participates in many chemical reactions
4- Why Is Water the Most Indispensable Nutrient?
- Almost a Universal solvent
- Dissolves amino acids, glucose, minerals, etc.
for transport
- Fatty substances are packaged with water-soluble
proteins
- Bodys cleansing agent
- Removes nitrogen wastes, before they build up to
toxic levels
- Kidneys filter wastes and excrete them as urine
5Why Is Water the Most Indispensable Nutrient?
- Water resists compression
- Acts as a lubricant and cushions joints
- Cushions spinal cord and fetus
- Lubricates the digestive, respiratory tract, and
tissues that are moistened with mucus
- Keeps pressure on the retina and lens
- Maintains body temperature
- Sweat cools the body via the skin, exhaled breath
and feces
6Water
0
- Water balance
- Intake needs to equal water loss
- Dehydration
- Water loss
- Progression of symptoms thirst ? weakness ?
exhaustion and delirium ? death
- Water intoxication
- Dilution of body fluids from excessive water
ingestion
- Symptoms headache, muscular weakness, lack of
concentration, poor memory, loss of appetite
7The Bodys Water Balance
- Bodys water content
- Varies by pounds at a time
- Especially in women who retain water during
menstruation
- High-salt meal leads to water retention
- Fluctuation in water weight does not reflect gain
or loss of body fat
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9How Much Water Do I Need to Drink in a Day?
- DRI meets 80 of days need for water
- Men 13 cups of fluid from beverages and drinking
water
- Women 9 cups of fluid from beverages and
drinking water
- Remaining water need is met from consumed foods
- Body produces water from the breakdown of
energy-yielding nutrients
10How Much Water Do I Need to Drink in a Day?
- Sweating increases water needs
- Doing physical work outdoors in hot weather
- An athlete in training
- Caffeine behaves as a diuretic
- The results of research is mixed
- People who habitually consume caffeine may adapt
to its diuretic effects
- An occasional caffeinated beverage can contribute
fluid to the body
11Are Some Kinds of Water Better for My Health
Than Others?
- Hard water
- High calcium and magnesium concentrations
- Soft water
- High sodium concentration
- There is some evidence that soft water may
aggravate hypertension and heart disease
- Mineral contaminants are more easily dissolved in
soft water--Cadmium, lead
- EPA is responsible for ensuring that public water
systems meet minimum standards for protection of
public health
12Consumer Corner Bottled Water
- 1 in 15 households use bottled water
- 250-10,000 times the cost of tap water
- Not safer than tap water
- 25 of bottled water is drawn from the tap
- FDA tests bottled water
- Standards substantially less rigorous than those
applied to U.S. tap water
13Body Fluids and Minerals
- Cells cannot directly regulate the passage of
water across their membranes
- Water content of cells is regulated by major
mineral salts dissolved in body fluids Salts are
charged articles (ions) called electrolytes
- The pumping of salts across their membranes
regulates cells water balance
- What are the salts??????
14Body Fluids and Minerals
- Salts are composed of charged articles (ions)
called electrolytes -potassium chloride, sodium
chloride
- When dissolved particles are separated by a
membrane water will flow to the side of greater
dissolved particle concentration
- This is how cells regulate their water content
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16Body Fluids and Minerals
- To control the flow of water, cells must expend
energy moving electrolytes from one compartment
to another
- Proteins pump mineral ions across cell membranes
- The result is fluid and electrolyte balance
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18Body Fluids and Minerals
- A disturbed fluid balance can cause a severe
illness
- In vomiting or diarrhea
- The loss of water from the digestive tract pulls
fluid from between the cells in every part of the
body ? water is lost from cell interiors
- Kidneys conserve water by increasing sodium
concentrations outside of cells ? more water loss
from cells
- Result fluid and electrolyte imbalance
19Body Fluids and Minerals
- Minerals play a role in acid-base balance
- In pure water H and OH- ions exist in
equilibrium
- When minerals are dissolved in water
- Some major minerals give rise to acids increased
H
- Other minerals give rise to bases increased OH-
- The maintenance of a nearly constant pH is
critical to life
- How much does the pH of the blood vary?????
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21Body Fluids and Minerals
- Some proteins and some mineral salts act as
buffers, molecules that gain or lose H ions as
needed to correct pH
- Kidneys help by excreting more or less H
- Lungs help by excreting more or less carbon
dioxide
- (Dissolved in the blood, carbon dioxide forms
carbonic acid)
22The Major Minerals
- Calcium
- Chloride
- Magnesium
- Phosphorus
- Potassium
- Sodium
- Sulfate
23Calcium
- Role
- Most abundant mineral in the body
- 99 stored in bone and teeth
- Part of bone structure
- Bone serves as a calcium reserve, releasing or
removing calcium from the blood
- Minerals of the bone are constantly forming and
dissolving
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26Calcium
- Role In Body Fluids
- 1 of calcium is in the fluids outside and
within cells
- Regulates the transport of ions across cell
membranes important in nerve transmission
- Helps maintain normal blood pressure
- Essential role in blood clotting
- Essential for muscle contraction (heartbeat)
- Secretion of hormones, digestive enzymes, and
neurotransmitters
- Activates cellular enzymes
27Calcium
- Role of calcium
- The body maintains a constant calcium
concentration in the blood
- The skeleton serves as a calcium reservoir
- Blood calcium is regulated by hormones
- When calcium intake is inadequate normal blood
calcium is maintained at the expense of the bones
28Calcium
- When calcium need increases
- Calcium absorption from the intestine increases
- Loss of calcium from the kidneys is reduced
- Adults absorb 25 of dietary calcium
- Percent increases as dietary calcium decreases
29Calcium
- Some bone loss is an inevitable consequence of
aging
- By the late 20s or 10 years after adult height is
reached, the skeleton no longer adds
significantly to bone density
- After 40 years of age, regardless of calcium
intake, bones begin to reduce density
- Loss can be slowed by a diet and physical activity
30Calcium
- To protect against bone loss, high calcium
intakes early in life are recommended
- A calcium-poor diet during the growing years may
prevent achieving peak bone mass
- Insufficient bone calcium increases the risk of
osteoporosis (adult bone loss)
- Recommended intakes are high for children and
adolescents
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32Phosphorus
- Second most abundant mineral in the body
- Concentration in the blood is less than half that
of calcium
- Role
- 85 is combined with calcium in the crystals of
the bone and teeth
- Phosphorous salts are buffers that help maintain
the acid-base balance of cellular fluids
- Part of DNA and RNA
- Phosphorus compounds carry, store, and release
energy of energy nutrients
- Phosphorous compounds assist enzymes and vitamins
in extracting the energy from nutrients
- Forms part of phospholipids
- Present in some proteins
33Phosphorus
- Need and deficiency
- Needs are easily met by almost any diet
- Deficiencies are unknown
- Source
- Animal protein is the best source
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35Magnesium
- Barely qualifies as a major mineral
- Only 1 ounce is present in the body of a
135-pound person
- Half in the bones
- The rest in muscles, heart, liver, other soft
tissues
- 1 in body fluids
36Magnesium
- Role
- Assists in the functioning of more than 300
enzymes
- Releases energy from energy-yielding nutrients
- Directly affects the metabolism of
- Potassium, Calcium, Vitamin D
- Acts in the cells of all soft tissue
- Making protein
- Releasing energy
- Works with calcium for the functioning of
muscles
- Promotes resistance to tooth decay by holding
calcium in tooth enamel
37Magnesium
- Deficiency
- Inadequate intake, Vomiting, Diarrhea,
Alcoholism, Protein malnutrition, Diuretic use
- Deficiency symptoms are rare in healthy people
- Toxicity
- Rare but can be fatal
- Only occurs with high intakes from Supplements or
magnesium salts
- May occur in older people who abuse
magnesium-containing laxatives, antacids, etc.
- Toxicity symptoms
- Severe diarrhea
- Acid-base imbalance
- Dehydration
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40Sodium
- Positive ion in sodium chloride (table salt)
- 40 of the weight of sodium chloride
- Role
- Fluid balance
- Electrolyte balance
- Maintenance of extracellular fluid balance
- Acid-base balance
- Muscle contraction
- Nerve transmission
41Sodium
- Deficiency
- No known human diet lacks sodium
- Most foods include more salt than is needed
- Body absorbs sodium freely
- Kidneys filter excess sodium out of the blood
into the urine
- Kidneys will also conserve sodium
- Small sodium losses occur in sweat
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43Sodium
- Sodium Intake
- Adults in the U.S. exceed the Tolerable Upper
Intake Level by more than a third
- Asian peoples, whose staple sauces and flavorings
are based on soy sauce and MSG, may consume the
equivalent of 30 to 40 grams of salt per day
44Sodium
- Sodium and Blood Pressure
- Communities with high salt intake experience high
rates of hypertension, cardiovascular disease,
and cerebral hemorrhage
- As sodium intake increases, blood pressure rises
- death from cardiovascular disease increases
- In salt-sensitive people, the more salt they eat
the higher their blood pressure
- People with diabetes, hypertension, kidney
disease
- People of African descent, those whose parents
had high blood pressure, and anyone over the age
of 50
45Sodium
- A dietary approach that may help salt-sensitive
and non-salt-sensitive people is the DASH diet
- This diet often achieves a lower blood pressure
than restriction of sodium alone
- DASH diet
- Greatly increased intake of fruits and
vegetables
- Adequate amounts of nuts, fish, whole grains,
low-fat dairy products
- Small portions of red meat, butter, and other
high-fat foods and sweets
- Salt and sodium are greatly reduced
46Sodium
- Low potassium intake raises blood pressure
- High potassium intake helps prevent and correct
hypertension
- Physical activity also lowers blood pressure
47Sodium
- Controlling Salt Intake
- The salt shaker may contribute as little as 15
of total salt consumed
- Processed and fast foods are the source of nearly
75 of salt in the U.S. diet
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49Potassium
- The main positively charged ion inside the bodys
cells
- Role
- Maintenance of fluid balance
- Maintenance of electrolyte balance
- Maintenance of cell integrity
- Maintenance of heartbeat
50Potassium
- Deficiency
- Causes sudden death
- Fasting or severe diarrhea in children with
kwashiorkor and people with eating disorders are
thought to be due to heart failure caused by
potassium loss - Low potassium intake
- Salt-sensitive hypertension becomes worse
- Metabolic acidity increases
- Calcium losses from bones accelerates
- Kidney stone risk increases
51Potassium
- Potassium intake
- In healthy people a reasonable diet provides
enough potassium to prevent dangerously low blood
potassium
- The typical U.S. diet, with low intakes of fruits
and vegetables, provides 50 of the DRI
- The richest sources of potassium are fresh, whole
foods
- Toxicity
- Potassium from food is safe
- Over-the-counter potassium chloride pills should
not be used except on a physicians advice
52Potassium
53Chloride
- Major negative ion in the body
- Role
- Accompanies sodium in fluids outside cells
- Acid-base balance
- Electrolyte balance
- Component of hydrochloric acid
- Source Salt
- Deficiency No known diet lacks chloride
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55Sulfate
- Role
- Required for the synthesis of sulfur-containing
compounds
- Antioxidants
- Thiamin, Biotin
- Sulfur-containing amino acids (cysteine)
- Help strands of protein assume their functional
shape
- Skin, hair, and nails
- DRI-none
- Deficiencies-Unknown
- Toxicity
- From too much sulfate in water contamination
56The Trace Minerals
- Role of trace elements often unknown
- An obstacle to determining the roles of trace
elements is giving an experimental diet lacking
the element to humans
- Most research has been limited to laboratory
animals
- Intake recommendations have been established for
nine trace minerals
- Others are recognized as being essential for some
animals but not proven required for humans
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58Iodine
- Role
- Component of thyroxin
- Made in the thyroid gland and is responsible for
the regulation of basal metabolic rate
- Deficiency
- Enlarged thyroid (goiter)
- Sluggishness
- Weight gain
59Iodine
- Severe deficiency during pregnancy
- Cretinism
- Irreversible mental and physical retardation of
the fetus
- Can be prevented if the deficiency is detected
and treated within the first six months of
pregnancy
- Iodine deficiency is one of the most treatable
and preventable causes of mental retardation
60Iodine
- Sources
- Seafood
- Iodine is plentiful in the ocean
- Iodized salt less than a half-teaspoon meets an
entire days recommendation
- Liberal use of iodized salt in fast-food and
other restaurant establishments
- Bakery products
- Milk 1 cup supplies nearly half of a days
recommended intake
- Toxicity
- Like chlorine and fluorine, deadly poison in
large amounts
61Iron
- Functions
- Oxygen transport as part of hemoglobin the
oxygen-carrying protein of red blood cells and
myoglobin the oxygen-holding protein of muscles
- Cofactor for enzymes
- Helps many enzymes use oxygen
- Needed to make
- New cells
- Amino acids
- Hormones
- Neurotransmitters
62Iron
- Food sources
- Red meats, liver, seafood
- Deficiency
- Iron-deficiency anemia
- Toxicity
- Poisoning in children
- Hemochromatosis
63Iron
- Iron loss
- Small amounts in
- Nail clippings
- Hair cuttings
- Shed skin cells
- Loss from bleeding can be significant
- Obtaining iron
- Only 10-15 absorption rate
- Rate increases with diminished body supply and
need (e.g. pregnancy)
- Decreases when iron is abundant
64Iron
- Iron deficiency
- Result of absorption not compensating for
losses or low dietary intakes
- Iron deficiency anemia
- Depletion of iron stores resulting in low
blood hemoglobin
- Symptoms of iron deficiency are often mistaken
for behavioral or emotional problems
- Some symptoms disappear when iron intake
improves
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66Iron
- Causes of Iron Deficiency and Anemia
- Malnutrition, inadequate iron intake
- Due to either a lack of food or high consumption
of the wrong foods
- In developed countries over consumption of foods
rich in sugar and fats and poor in other
nutrients
- Non-nutritional causes of anemia
- Most often blood loss
- Due to menstrual loss, women lose 1.5x as much
iron as men
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68Iron
- Causes of Iron Deficiency and Anemia
- Women are at greater risk of an iron deficiency
than men
- Need more iron-- menstruating and pregnant women
have increased iron needs
- On average, eat less food
- Infants over 6 months of age, young children,
adolescents, have increased iron needs
- To support growth of new tissue
69Iron
- Worldwide, iron deficiency is the most common
nutrient deficiency
- Affecting more than 1.2 billion people
- In developing countries parasitic infections of
the digestive tract cause people to lose blood
daily
- In the digestive tract, ulcers, sores, and
inflammation can cause blood loss
- In developing countries, almost half of preschool
children and pregnant women suffer from
iron-deficiency anemia
70Iron
- In the U.S., iron deficiency affects 10 of
toddlers, adolescent girls, and women of
childbearing age
- The iron status of infants and young children has
improved over the last decade
- Due to increased breastfeeding, which promotes
iron absorption, and greater use of
iron-fortified infant formula and cereals
- For low-income families, WIC provides coupons
redeemable for foods high in iron
71Iron
- Can a Person Take In Too Much Iron?
- Iron is toxic in large amounts
- Once absorbed it is difficult to excrete
- The body defends against iron overload
(hemochromatosis) by controlling its entry
- Intestinal cells trap some of the iron and when
these cells are shed the excess iron they
collected is lost from the body
- When iron stores fill up less is absorbed
- Iron overload has a strong genetic component
- May occur more often than previously expected
- Especially among Caucasians
72Iron
- In hereditary iron overload, the intestine
continues to absorb iron at a high rate despite
excess iron building up in body tissues
- Early symptoms are fatigue, mental depression,
abdominal pains
- Later, tissue damage occurs, with liver failure,
abnormal heart beats, diabetes
- Infections are likely because bacteria thrive on
iron-rich blood
73Iron
- The danger of iron overload is an argument
against high-level iron fortification of foods
- Susceptible people would have trouble following a
low-iron diet if most foods were dosed with iron
- There is a tendency in the U.S. to take vitamin C
supplements, further increasing iron absorption
- Iron-fortified foods pose no risk for healthy
people
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75Iron
- Iron Recommendations and Sources
- Vegetarian sources of iron are not well absorbed
- Vegetarians are advised to obtain 1.8 times the
normal requirement
- To meet iron needs, is best to rely on foods
- Iron from supplements is not absorbed as well
- Pregnant women need an iron supplement
- Iron supplements should be taken when recommended
by a physician
- Iron supplements can reverse iron-deficiency
anemia from dietary causes
76Iron
- Absorbing Iron
- Iron occurs in two forms in foods
- heme iron
- The iron-containing part of hemoglobin and
myoglobin in meat, poultry and fish
- Heme iron is more easily absorbed than nonheme
iron
- nonheme iron
- Found in foods from plants
- Vitamin C can triple absorption of nonheme iron
77Iron
- Interference of iron absorption
- Tannins
- Found in tea and coffee
- Calcium and phosphorus
- Milk
- Phytates
- Found in the fiber of lightly processed legumes
and whole-grain cereals
- Black tea reduces iron absorption--people with
iron overload are advised to drink it with their
meals
78- Cooking in an iron pan adds iron to food
- This iron is in the form of iron salts somewhat
like those in supplements
- The iron content of 100 grams of spaghetti sauce
- Simmered in a glass dish 3mg
- Cooked in a black iron skillet 87mg
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80Zinc
- Role
- Works with proteins in every body organ
- Helps nearly 100 enzymes to
- Make parts of the cells genetic material
- Make heme in hemoglobin
- Assist the pancreas with its digestive functions
- Metabolize carbohydrate, protein, and fat
- Liberate vitamin A from storage in the liver
- Regulates gene expression in protein synthesis
- Affects behavior and learning
- Assists in immune function
- Assists in wound healing
81Zinc
- Role (continued)
- Sperm production
- Taste perception
- Fetal development
- Growth and development in children
- Produces the active form of vitamin A in visual
pigments
82Zinc
- Deficiency symptoms
- Adverse affects on growth
- Alters digestive function
- Causes diarrhea, worsens malnutrition
- Impaired immunity
- Abnormal taste
- Abnormal vision in the dark
- Toxic in large quantities
- In high enough doses, supplements can cause
serious illness or death
- Cause infections
- High doses can also inhibit iron absorption
83Zinc
- Zinc and iron are are often found together in
foods
- Food sources never cause imbalances in the body
- Zinc from lozenges and spray, sold for the
treatment of the common cold, may or may not
provide the intended relief
- Contributes supplemental zinc to the body
84Zinc
- Food Sources
- Meats
- Shellfish
- Poultry
- Some legumes
- Whole grain
- Requirements
- Men 11 mg/day
- Women 8 mg/day
- Vegetarians are advised to eat a varied diet that
includes whole-grain breads leavened with yeast
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86Selenium
- Role
- Protects body chemicals against oxidative damage
- Assists a group of enzymes that, in concert with
vitamin E, work to prevent the formation of free
radicals and prevent oxidative harm to cells and
tissues - Plays roles in activating thyroid hormone
- Low blood selenium correlates with the
development of some forms of cancer
- Especially prostate cancer
87Selenium
- Sources
- Widely distributed in foods such as
- Meats
- Shellfish
- Vegetables and grains grown in selenium-rich
soils
- Toxicity
- Long-term supplementation
- Symptoms
- Hair loss
- Diarrhea
- Nerve abnormalities
- UL 400 micrograms/day
88Fluoride
- Not essential to life
- Only a trace occurs in the human body
- Role
- Helps prevent dental caries
- Sources
- Primary source fluoridated drinking water
- 65 of U.S. population has access to water with
optimal fluoride concentration
- Rarely present in bottled water
89Chromium
- Role
- Works closely with insulin to regulate and
release energy from glucose
- Deficiency
- Impaired insulin action
- Supplements cannot cure diabetes
- Research is being done on the role of chromium
supplements in the management of type 2 diabetes
- Source
- Widely distributed in the food supply
- Especially in unrefined foods and whole grains,
liver, nuts, cheeses
90Copper
- Role
- Formation of hemoglobin and collagen
- its oxygen-handling ability
- the bodys handling of iron
- the release of energy
- Deficiency
- Rare
- Seen in severely malnourished infants fed a
copper-poor milk formula
- Excess zinc interferes with copper absorption and
can cause deficiency
- Symptoms
- Can severely disturb growth and metabolism
- In adults can impair
- Immunity
- Blood flow through arteries
91Copper
- Toxicity
- Unlikely from foods
- Can be caused by supplementation
- UL for adults 10 mg/day
- Sources
- Organ meats
- Seafood
- Nuts
- Seeds
- Water may supply copper
- Especially where copper plumbing pipes are used
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93Other Trace Minerals
- Boron
- Influences the activity of many enzymes
- Molybdenum
- Functions as a part of several metal-containing
enzymes
- Manganese
- Works with dozens of different enzymes
94Other Trace Minerals
- Cobalt- Part of B12/Cobalamin
- Nickel- Important for the health of many body
tissues
- Silicon- Bone calcification in animals
- Future research may reveal key roles played by
- Barium, Cadmium, Lead, Lithium Mercury, Tin,
Vanadium, Arsenic
95Trace Minerals
- Research on trace minerals
- Uncovering interactions
- An excess of one may cause a deficiency of
another
- For example, a slight manganese overload may
aggravate an iron deficiency
- A deficiency of one mineral may cause another to
have a toxic reaction
- For example, iron deficiency makes the body more
susceptible to lead poisoning
96Food Feature Meeting the Need for Calcium
- Calcium consumption
- Average woman consumes one-third of her
recommended calcium intake
- Average man consumes close to three-fourths of
recommendation
97Food Feature Meeting the Need for Calcium
- Deficiency
- Associated with all sorts of major illnesses
including
- Adult bone loss
- High blood pressure
- Kidney stones
- Lead poisoning
- Consumption of milk, one of the best sources of
calcium, has declined
- While the consumption of beverages such as soft
drinks has dramatically increased
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99Food Feature Meeting the Need for Calcium
- Sources
- Milk, Yogurt, and Cheese Group
- Yogurt, Kefir, Buttermilk, Cheese
- Especially low-fat or fat-free varieties
- Ice cream
- For those who can afford the calories
- Cottage cheese and frozen yogurt desserts contain
about half the calcium of milk
- Butter, cream, and cream cheese are almost pure
fat and contain negligible calcium
1000
- Food Feature Meeting the Need for Calcium
- Sources contd
- Add cocoa to milk
- Sugar adds both sweetness and calories
- Add fruit to yogurt
- Make fruit smoothies from milk or yogurt
- Add fat-free milk powder to any dish
- Rutabaga, Broccoli, Beet, Collard Greens, Turnip
Greens, Bok Choy, Kale Greens, Cabbage, Kohlrabi,
Watercress, Parsley, Some Seaweeds
- Small fish such as sardines and other canned fish
their bones are rich sources of calcium
- One-third cup of almonds supplies 100 mg
calcium
-
101Food Feature Meeting the Need for Calcium
- Spinach, Swiss chard, rhubarb
- Provide little calcium to the body because they
contain binders that prevent calcium absorption
- Spinach good source of
- Iron, Beta-carotene, and dozens of other
essential nutrients and phytochemicals
- Dark greens good source of
- Riboflavin --Good for vegans or persons who dont
drink milk
102Food Feature Meeting the Need for Calcium
- Sources continued
- Stocks or extracts made from bones
- Vietnamese tradition of making fish stock from
the bones helps account for their adequate
calcium intake without the use of milk
- Calcium-rich mineral water may be a useful
source
- Recent evidence seems to indicate that calcium
from mineral water, including hard tap water, may
be as absorbable as the calcium from milk
103Food Feature Meeting the Need for Calcium
- Sources continued
- Processed Food
- Soybean curd
- Tofu
- Calcium salt is often used to coagulate it
- Canned tomatoes
- Firming agents donate about 63 mg/cup
- Stone-ground and self-rising cornmeal
- Blackstrap molasses
104Food Feature Meeting the Need for Calcium
- Fortified sources
- Calcium-fortified orange juice
- 300 mg/8 ounces
- Bioavailability is comparable to that of milk
- Milk fortified with additional calcium
- 500 mg/8 ounces
- Soy milk
- Can be prepared so that it contains more calcium
than cows milk
- Supplements
- While useful are not guaranteed to ward off bone
loss
105ControversyOsteoporosis Can Lifestyle Choices
Reduce The Risks?
- More than 28 million people in the U.S. suffer
from osteoporosis
- Many of them women
- Men are not immune to this disease
- Each year 1.5 million people suffer broken hips ,
30 are men
- As a result of osteoporosis people also suffer
breaks of the pelvis, legs, arms, hands, and
ankles
106Osteoporosis
- Causes of osteoporosis
- Insufficient dietary calcium plays a role
- Lack of Physical activity
- Gender
- Advanced age
- Genetics
- Environmental factors
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109Osteoporosis
- Trabecular bone is more metabolically active than
cortical bone--Calcium loss begins in
mid-twenties for men and women
- Cortical bone --Calcium is lost slowly and begins
at about age 40
- As bone loss continues and osteoporosis
progresses
- Vertebrae may disintegrate, wrists may break,
teeth may loosen or fall out, breaks often occur
in the hip
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112Osteoporosis
- Causes of Osteoporosis
- Gender
- Advanced age
- Genetics
- Environmental factors
113Osteoporosis
- Environmental factors under study for their role
in lowering bone density include
- Poor nutrition
- Lack of calcium and vitamin D
- Estrogen deficiency in women
- Lack of physical activity
- Use of tobacco and alcohol
- Possibly excess protein, sodium, caffeine, soft
drinks
- Inadequate vitamin K intake
- Underweight
114Osteoporosis
- Genetics studies include identical twins
- A study of elderly Finnish twins suggests that
fracture rates vary between twin siblings
- Your genes may provide an inherited tendency for
strong or weak bones
- But is affected by individual life experiences
115Osteoporosis
- Risks of osteoporosis differ by race and
ethnicity
- People of African descent have denser bones than
do those of northern Europeans
- Mexican Americans bone density falls somewhere
between
- Hip fractures are 3x more likely in 80-year-old
white women than in black women of the same age
116Osteoporosis
- Women who seldom drink milk as children or
teenagers
- Have lower bone density and greater risk of
fractures than those who drank milk regularly
- In childhood, those who avoid drinking milk may
be more prone to fractures than their
milk-drinking peers
- Dietary calcium and vitamin D in later years
cannot make up for earlier deficiencies
117Osteoporosis
- Older people take in less calcium and vitamin D
than others
- After about age 65, people absorb less calcium
- Aging skin is less efficient at making vitamin D
- go outdoors less
- Some of the hormones that regulate bone
maintenance and calcium metabolism also change
with age and accelerate bone mineral withdrawal
118Osteoporosis
- Gender and Hormones
- Men have greater bone density than women at
maturity
- Women have greater bone loss during menopause
- Women account for more than 2/3 of cases of
osteoporosis
- Bone loss is rapid when estrogen drops during
menopause
- Accelerated losses continue for 6 to 8 years
following menopause and then tapers off but
continues
119Osteoporosis
- Men produce only a little estrogen, but have less
osteoporosis than women
- Testosterone may play a role
- Men suffer more fractures after removal of
testes or when their testes lose function with
aging
- Physical Activity
- When people are idle the bones lose strength just
as the muscles do
- Astronauts who live without gravity for days or
weeks at a time experience rapid and extensive
bone loss
120Osteoporosis
- Muscle use promotes bone strength
- The bones of active people are denser than those
of sedentary people
- Hormones that promote synthesis of new muscle
tissue also promote the building of bone
- Flexibility and muscle strength improve balance
and help prevent falls
- Do weight bearing activities and exercise!!!!!
121Osteoporosis
- Body Weight-- Heavier body weights and higher
body fatness stress the bones and promote their
maintenance
- Tobacco Smoke and Alcohol --cause bones to be
less dense
- Protein Excess --causes the body to excrete
calcium in the urine especially when calcium
intake is low
122Osteoporosis
- Sodium, Caffeine, Soft Drinks, Vitamin K,
Homocysteine
- There is research associated with the effects of
each of these substances and their possible link
to osteoporosis
123Osteoporosis
- Homocysteine
- Elevated blood levels of this amino acid
indicates a dietary deficiency of Folate, Vitamin
B12, Vitamin B6
- Netherlands study
- People with the highest homocysteine levels
experienced 2x as many hip and wrist fractures as
people with lower levels
- U.S. study
- Rate of hip fractures quadrupled in men and
doubled in women with the highest homocysteine
levels
124Osteoporosis
- Homocysteine
- Not clear if elevated levels contribute to
osteoporosis or if it exist as an innocent
bystander
- Magnesium
- Helps maintain bone density
- Vitamin A
- Needed in the bone-making process
- Too much may be associated with osteoporosis
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126Osteoporosis
- Diagnosis
- Use of DEXA or ultrasound as well as
- Men with a family history of osteoporosis and all
women should have a bone density test after they
reach age 50
127Osteoporosis
- Medical Treatment
- Estrogen therapy for non-menstruating women can
help prevent further bone loss and reduce the
incidence of fracture
- Such therapy may increase the risks for heart
disease and breast cancer
- Several drugs are available that can help reverse
bone loss
- These drugs inhibit the activities of
bone-dismantling cells
128Osteoporosis
- Calcium Recommendations
- Adequate calcium nutrition during the growing
years is essential to achieving optimal peak bone
mass
- Only 10 of girls and 25 of boys meet the
recommendations for calcium during their
bone-forming years
- DRI
- 1,300 mg/day for ages 9-18 years
- Amount of calcium in 4 cups of milk
- 1,000 mg/day through age 50
- 1,200 mg/day after age 50
- Calcium should be obtained from foods and
beverages
129Osteoporosis
- Calcium and vitamin D supplements after the age
of 50 produce small but beneficial effects on
bone mass and fracture rates
- During the menopausal years, calcium supplements
of 1 gram may slow, but cannot fully prevent,
bone loss
130Osteoporosis
- Calcium Supplements
- Purified calcium compounds
- Calcium carbonate
- Calcium citrate
- Calcium gluconate
- Calcium hydroxide
- Calcium lactate
- Calcium malate
- Calcium phosphate
- Calcium with amino acids
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132Osteoporosis
- The UL for calcium is set at 2,500 mg
- Supplements should provide less than this
- Foods also provide calcium
- The Consensus Conference on Osteoporosis
recommends milk
- The American Society for Bone and Mineral
Research recommends foods as a source of calcium
in preference to supplements
- The NIH concludes that foods are best and
recommends supplements only when the intake from
food is insufficient