Microbial Therapy (Steph, Alex, Sammy) Pathway Engineering

1
Brainstorming Session Overview Useful
Applications of Synthetic Biology
Medical / Human Applications
BioEnergy
Microbial Therapy (Steph, Alex, Sammy) Pathway
Engineering - make product body needs
(possibly sense deficiency) - Synthetic
Symbiosis (E. coli natural gut environment)
- Vitamin B Production (Steph and Alex) -
Fibrin (clotting) (Sammy) - Insulin (Harris)
- Degrade Plaque - Implantable Devices that
release or synthesize drugs - Off-switch for
safety, competitive concerns (Alex) Cellular
Targeting - Aptamers (Steph) - Bacterial
Surface Display / Fusion Prot. (Perry) - Target
Bact to certain tissues (actuator or product) -
Targeting Microbial Factories - Sequestration
of Toxic Compounds (Sammy) Bacterial Biosensors
- Sense and Sequester Toxic Compounds
(arsenic) (Sammy) - Quorum Sensing - Radon
Sensor Biofilms and Vascularization (Harris and
Sammy) Recombination (Harris)
Producing a Renewable Energy Source Cellulose to
EtOH (Shaunak, Steph, Alex) Fatty Acid
production and degradation for energy Synthesis,
Tolerance, and Export of EtOH or
alkanes Alternative organisms for Energy Prod.
Yeast (Shaunak) Bacteria as Energy Source Light
Powering E. coli w/ Photorhodopsin
(Alex) Powering Implantable Medical
Devices Light sensitive Proton Pump (Pseud.
Putida) Biological Based Fuel Cells (Sammy)
Bridging Applications
E. coli that resists mutations (Alex) Cellular
Computation (George) Microfluidics (George) DNA
transfer using virus (Shaunak) Combinatorial
Constructions and Selections BioBricks (Nick)