Cholesterol de novo synthesis I Isoprenyl formation - PowerPoint PPT Presentation

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Cholesterol de novo synthesis I Isoprenyl formation

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Cholesterol de novo synthesis I. Isoprenyl formation. Acetoacetyl-CoA. Thiolase. HMG-CoA ... 3-Hydroxy-3- methylglutaryl-CoA. Mevalonate. kinase ... – PowerPoint PPT presentation

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Title: Cholesterol de novo synthesis I Isoprenyl formation


1
Cholesterol de novo synthesis IIsoprenyl
formation
2 NADPH
2 NADP
Thiolase
HMG-CoAsynthase
HMG-CoAreductase
3-Hydroxy-3-methylglutaryl-CoA
Acetoacetyl-CoA
Mevalonate
Mevalonatekinase
3, 3-Dimethylalylpyrophosphate
Isomerase
ATP
ADP
Mevalonate-5-pyrophosphodecarboxylase
Phosphomevalonatekinase
ATP
ATP
ADP
5-Phosphomevalonate
ADP
3-Isopentenylpyrophosphate
5-Pyrophosphomevalonate
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