International Qualex Flow Cytometry Systems

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International Qualex Flow Cytometry Systems
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Detection Products

• FMK Inhibitor based caspase detection
• Fluorescence labeled inhibitors.
• All reagents are cell permeant and require no
  cell lysis, permeabilization steps or antibodies
• Analysis by fluorescence microscopy, fluorescence
  plate reader or flow cytometry
• Products for poly caspases and individual
  caspases 1, 2, 3/7, 4, 5, 6, 8, 9, and 10

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Movie
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Movie
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Neuroblastoma Cell
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Normal Keratoconus corneal fibroblasts
Cristina Kenney, M.D., Ph.D.
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Drosophila eye
Rebecca Hays Ph.D
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Correlation between our reagent and Annexin
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FLICA vs. TUNEL
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Apoptosis vs. Necrosis
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Apoptosis vs. Necrosis
7-AAD
FAM-VAD
FAM-VAD
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Apoptosis vs. Necrosis
7-AAD
FAM-VAD
FAM-VAD
Protein A
Protein B 12 h
post inoculation
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Apoptosis vs. Necrosis
7-AAD
FAM-VAD
FAM-VAD
Protein B 24 h Post inoculation
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In vivo apoptosis detection
Patent Pending
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Morphine enhanced apoptosis in splenocytes
Morphine LPS LPS Morphine Control
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Morphine enhanced apoptosis in bone marrow
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Tissue
Control mice LPS only
mice Morphine LPS
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(No Transcript)
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Chemotherapeutic efficacy
Mice receive 8 mg/kg of Arsenic Trioxide (ATO)
Robert Griffen Ph.D
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SR-VAD-FMK
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FAM-VAD-FMK
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Confirmation by Flow Cytometry
ATO 8.0 mg/kg 39 Apoptotic
Control 18 Apoptotic
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Bird brain in vivo
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Neurodegeneration
. P.E. Paulson, Ph. D
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chemotherapyefficacy
Eyedisease
Neuro-degeneration
Cardiac damage