CLINICAL SUMMARY SKIN CANCER IN ORGAN TRANSPLANT PATIENTS

1
CLINICAL SUMMARYSKIN CANCER IN ORGAN TRANSPLANT
PATIENTS

• ORGAN TRANSPLANT RECIPIENTS HAVE A HIGH RATE OF
  SKIN CANCER WITH AN ELEVATED RISK OF
  METASTASIS AND DEATH
• RISK FACTORS FOR LIFE THREATENING SKIN CANCERS
  INCLUDE
• USE OF MULTIPLE IMMUNOSUPPRESSIVES, A PAST
  HISTORY OF
• SKIN CANCER, FAIR SKIN, EXTENSIVE PREVIOUS
  SUN EXPOSURE
• OR THOSE TRANSPLANTED BEFORE AGE 18
• CONSIDER MINIMIZING IMMUNOSUPRESSION AND
  INCLUDING RAPAMYCIN OR ORAL RETINOIDS IN THE
  REGIMEN FOR AT RISK PATIENTS
• TRANSPLANT PATIENTS WHO ARE AT RISK FOR SKIN
  CANCER SHOULD HAVE ROUTINE SCREENINGS BY A
  DERMATOLOGIST
• PHOTOPROTECTION SHOULD BE EMPHASIZED PRE AND
  POST TRANSPLANT

References1. Berg D, Otley CC Skin cancer in
organ transplant recipients Epidemiology,
pathogenesis, and management Journal of
the American Academy of Dermatology July 2002
(Vol. 47, Issue 1, Pages 1-17) 2. Wright TI,
Spencer JM, Flowers FP Chemoprevention of
non-melanoma skin cancer Journal of the
American Academy of Dermatology June 2006 (Vol.
54, Issue 6, Pages 933-946)