Title: Presentacin de PowerPoint PO67
1PO-67 M. Martinez-Rebollar et al.
Objective To identify factors associated with
virological, immunological and clinical outcome
in naïve patients who have initiate HAART from
January 1997 to December 2006.
- Methods
- Retrospective cohort study
- Including all antiretroviral naïve patients who
have initiate HAART from 1997 to 2006 in a
tertiary hospital in Barcelona. - Evaluate by calendar year (1997-00, 2001-03 and
2004-06) and CD4 strata (lt200, 201-350 and 350) - The demographic and clinical characteristics at
the initiation of HAART - The composition of the antiretroviral regimen
- CD4 response
- Clinical outcome (development of new AIDS events
and/or non-AIDS related mortality) using a
multivariate analysis.
2PO-67 M. Martinez-Rebollar et al.
Results Adjusted Hazard Ratio (95CI) of
progression to aids and death
Sex, age, VL at baseline, type of ARVc regimen,
risk factor were also evaluated but not included
in the final model
3PO-67 M. Martinez-Rebollar et al.
Conclusions
- In HAART era, the response to initial
antiretroviral therapy in terms of CD4 rise,
clinical outcome and survival has gradually and
significantly improved. - But remain significantly worse among older
patients and late presenters. - HAART should be initiated, at least, when CD4
cell count drop lt 350.
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