Translational Medicine Information Needs Driving Change

1
Translational Medicine Information Needs
Driving Change

• Vijay Pillai
• Oracle Corporation
• May 4, 2006

2
The Evolution Information Driven
Today
Tomorrow

• Biology Laboratory science
• Volumes of disparate islands of data
• RD activities based on minimal clinical
  information
• Healthcare primarily paper based
• Limited ability to track and report on disease
  outbreaks
• One drug for entire population
• Agriculture output dependant on crop yield and
  pest infestation

• Biology Information science
• Seamless data integration and knowledge
  management
• RD based on real time clinical information
• Electronic data collection and analysis to
  improve patient care
• Patient admission diagnosis analyzed to preempt
  outbreaks
• Drugs for targeted populations
• Genetically modified crops with high yields
  disease resistant

3
Timely Access To Clinical Information is Key for
Informed Decision Making
Specialists
4
Same Data Multiple Subscribers

• Clinical research
• Best therapy for cost
• Trial Candidate selection
• Drug performance
• Best practices

• Cohort identification
• Drug performance
• Pharmaco-vigilance
• Outcomes analysis

Specialists

• Best therapy for cost
• Drug performance
• Best practices

• Pharmaco-vigilance
• Drug safety
• Regulations

5
Need for Blending Applied Science with Discovery
Science
Clinical Applications
Research Applications
New ClinicalProducts
ResearchTools
6
Blending of Applied Science with Discovery
Science Impact on the Information Platform
Clinical Pathways
DNA Profile
Diagnosis / Outcomes
Prescription Records
Expression Profile
Samples
Medical Images Reports
Pathways
- Healthcare
- Life Sciences
7
Blending of Applied Science with Discovery
Science Impact on the Information Platform
Diagnosis / Outcomes
Clinical Pathways
DNA Profile
Healthcare Transaction Base
Technology Gap
Samples
Expression Profile
Medical Images Reports
Prescription Records
Pathways
Need for a proven platform to store and analyze
complex data sets
- Healthcare
- Life Sciences
8
Need for a Standards Based Platform
Diagnosis / Outcomes
Clinical Pathways
DNA Profile
Healthcare Information Platform
Samples
Expression Profile
Medical Images Reports
Prescription Records
Pathways
Patient centric, standards based, interoperable
information
9
What the Future Holds
Diagnosis / Outcomes
Clinical Pathways
DNA Profile
Healthcare Information Platform
Samples
Expression Profile
Medical Images Reports
Prescription Records
Pathways
More accurate cohorts for candidate selection
Real-time clinical info
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National Healthcare Information
Network(Conceptual Architecture)