Pacman Flux Segregates Chromosomes

1
Pacman / Flux Segregates Chromosomes
Cartoon of a Mitotic Half-Spindle
Dan Buster AECOM
2
Pacman / Flux Segregates Chromosomes
Both Flux and Pacman can contribute to Anaphase A
Dan Buster AECOM
3
Pacman / Flux Segregates Chromosomes
Flux and Pacman rates measurable
after photobleaching fluorescent microtubules.
Video
Dan Buster AECOM
4
Removal of Inhibitory Cap?
Katanin required for Pacman in S2 cells.
Recruitment of Pacman Components?
CLIP-190 required for Pacman in S2 cells.
Driving Pacman
Dan Buster AECOM
KLP59D required for flux and Pacman in S2 cells.