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Psyc 2301 P05

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Dopamine cannot cross blood-brain barrier ... Death of Heath Ledger: 'Anti-Anxiety,' 'Sleeping Pills,' and Anti-Histamines. Imaging (p. 69) ... – PowerPoint PPT presentation

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Title: Psyc 2301 P05


1
Psyc 2301 P05 P06
  • Professor Baggette

2
Announcements
3
Psyc 2301 P05 P06 Today
  • Chapter 2 (Wrapup)
  • Chapter 3 (Nature v Nuture)

4
Chapter TwoNeuroscience
5
But, first, review from Last Time
6
Key Topics from Neuro
  • Parkinsons, L-Dopa, and Dopamine
  • Meth Schizophrenia (Dopamine)
  • Addiction Definition
  • Addiction Homeostasis, Withdrawal, Tolerance
  • GABA, Benzodiazepines, Alcohol

7
Parkinsons, L-Dopa, and Dopamine (p. 58)
  • Parkinsons Motor Tracts of the brain
    (substantia nigra) begin to fail to produce
    enough dopamine
  • Dopamine cannot cross blood-brain barrier
  • L-Dopa (precursor to Dopamine) administered to
    counteract symptoms

8
Alzheimers Endorphins (p. 58)
  • Please read each of these topics, in the book, on
    p. 58 know for test
  • Know about Alzheimers Ach
  • Know about Endorphins Pain

9
Meth and Schizophrenia
  • Parkinsons, Meth Schizophrenia all interact
    with Dopamine
  • Excessive Dopamine (or similar effect) is the
    result of Meth usage excessive Meth usage
    produces symptoms similar to Schiz
  • Excessive L-Dopa can produce same results in
    Parkinsons patients

10
Addiction Defined
  • Drug Seeking Behavior
  • Contrary to popular belief, actual usage is a
    very small part of addiction
  • Drug seeking behavior and lifestyle are the
    predominant factors
  • Non-Using Friends and Family sometimes have
    greater problems than the addicts

11
Addiction Homeostasis, Withdrawal, Tolerance
  • Two Definitions of Homeostasis
  • Physiological Balances, such as body temperature,
    fluid electrolyte balance, blood sugar, Oxygen
    Carbon Dioxide in Body, etc.
  • Balance of Relationships in Family Therapy

12
Addiction Homeostasis, Withdrawal, Tolerance
  • Tolerance More is needed to achieve the same
    effect
  • Withdrawal Balance (Homeostasis) of body becomes
    imbalanced as a result of removal of something.
  • Withdrawal Anxiety if a Benzo is removed Sleep
    if Meth or Cocaine

13
Please be familiar with this diagram (p. 55)
14
Please be familiar with this diagram (p. 57)
15
Please be familiar with this diagram (p. 60)
16
GABA, Benzodiazepines, Alcohol
  • GABA Gamma Amino Butyric Acid
    Neurotransmitter
  • Alcohol Beer, Wine, Liquor
  • Benzodiazepines Librium, Valium, Klonopin,
    Xanax
  • Stimulates Parasympathetic Nervous System

17
Benzodiazepines
  • Prescription Medications
  • Highly Addictive
  • Extremely Dangerous to Mix with Alcohol
  • Librium
  • Valium
  • Klonopin
  • Xanax

18
New Material
19
Key Topics from Neuro (cont.)
  • Spinal Cord and Reflex Arcs
  • Autonomic Nervous System Function and
    Characteristics of both Sympathetic and
    Parasympathetic Nervous Systems
  • Imaging CAT, PET, fMRI
  • Basic Brain Anatomy Brainstem Medulla Limbic
    System, Cerebellum, Cerebrum
  • Four Lobes of Frontal Cortex

20
Spinal Cord and Reflex Arcs (p. 63)
21
Spinal Cord and Reflex Arcs (p. 63)
  • Reflex Action / Processing Stages
  • Sensory Neuron
  • Interneuron in Spinal Cord
  • Motor Neuron
  • Know that Reflexes are processed through the
    Spinal Cord

22
Autonomic Nervous System (p. 62)
23
Autonomic Nervous System (p. 62)
  • Sympathetic Fight or Flight Meth Cocaine
    Dilation of Pupils
  • Parasympathetic Rest (Sleep) Digest
    Lacrimation Alcohol and Benzodiazepines
    Constriction of Pupils
  • Death of Heath Ledger Anti-Anxiety, Sleeping
    Pills, and Anti-Histamines

24
Imaging (p. 69)
  • CAT Scans Computerized Axial Tomography serial
    X-Rays reassembled into 3D by computer
  • PET Radioactive tracer glucose used to measure
    most active parts of brain during a task
  • fMRI newest similar to PET but no tracer read
    about fMRI and lying (p. 70)

25
fMRI Lying (p. 70)
26
Basic Brain Anatomy (p. 70)
  • Brainstem Medulla Heartbeat Respiration (in
    all vertebrates, including fish) (p. 71)
  • Limbic System seat of emotions (amygdala)
    short term memory (hippocampus antereograde
    amnesia) (p. 72)
  • Cerebellum Motor skills, especially ballistic
    movement (p. 72)
  • Cerebrum Higher Cognitive Functions

27
Four Lobes of Frontal Cortex (p.76)
28
Four Lobes of Frontal Cortex (p.76)
  • Frontal Higher Cognitive Functions
  • Temporal Auditory Short Term Memory Emotional
    Processing (along w/ limbic)
  • Parietal Sensory input for touch body position
  • Occipital Initial Visual Processing from Eyes
    (Coupe Counter-Coupe Injury)

29
Chapter ThreeNature v. Nurture
30
Basic Human Genetics (p. 97)
31
Basic Human Genetics
  • Somatic Cells have 46 Chromosomes
  • Germ Cells have 23 Chromosomes

32
Genetic Diseases
  • Two major categories of genetic diseases
  • One major category of genetic disease involves
    point mutations (which result from errors in
    replication of DNA)
  • The other major category involves extra, missing,
    or malformed chromosomes

33
Point Mutations
  • Sickle Cell Disease may have an adaptive
    function related to malaria
  • Tay-Sachs Disease
  • Cystic Fibrosis
  • Charcot-Marie-Tooth Disease
  • The list of diseases related to point mutations
    is very long

34
Chromosomal Abnormalities
  • Trisomy 21, the basis of Downs Syndrome, is
    probably the most common autosomal disorder
  • Many chromosomal abnormalities cause a fetus to
    abort in utero. (We have little chance to study
    or understand them.)

35
Chromosomal Abnormalities
  • Trisomy 18 is called Edwards Syndrome, is rarer
    than Downs, and is more lethal (only 10 of
    babies live past birth)
  • Trisomy 13 (Pataus Syndrome) even rarer than
    Edwards
  • Many chromosomal abnormalities cause a fetus to
    abort in utero. (We have little chance to study
    or understand them.)
  • Only three trisomies are known 21, 18, 13

36
Sex Chromosomes
  • Human beings have 44 autosomal chromosomes and 2
    sex chromosomes
  • Human Males have one X chromosome and one Y
    chromosome
  • Human Females have two X chromosomes
  • The only known function of the Y chromosome
    occurs in utero (see, also p. 130)

37
A human egg contains _____ chromosome and a human
sperm contains ______
  • A Y either an X or a Y
  • Either an X or a Y an X
  • An X either an X or a Y
  • Either an X or a Y a Y

38
A human egg contains _____ chromosome and a human
sperm contains ______
  • A Y either an X or a Y
  • Either an X or a Y an X
  • An X either an X or a Y
  • Either an X or a Y a Y

39
Brain Development
  • A side effect of the action of the Y chromosome
    in utero (testosterone generation) is to cause
    male brains to develop asymmetrically
  • Neuroscientists believe that the asymmetrical
    development of a male brain gives advantages in
    visual-spatial processing
  • Female (symmetrical) brains appear to have an
    advantage in verbal processing (speech language)

40
Twin Studies (p. 98)
41
Twin Studies
  • Twin Studies were very popular in the early 20th
    Century
  • Twin studies fell out of favor due to discovery
    of fraudulent research
  • Twin studies are back
  • Fraternal twins are genetically equivalent to any
    other brother or sister
  • Identical twins are clones

42
Twin Studies (p. 98)
43
Identical Twins (p. 99)
44
Identical Twins
  • Several anecdotal stories indicate remarkable
    similarities between twins
  • Twins raised together will still have a certain
    amount of variety
  • Comparing twins raised apart to twins raised
    together can provide important clues to the
    influence of heredity

45
Environment
  • The textbook references the work of Rosenzweig on
    rats (p. 114-115)
  • Book Enriching Heredity by Marian Diamond
  • The result of an enriched environment was a
    thicker neocortex in the subjects that reflected
    increased numbers of synapses
  • Know that loss of unused neural connections are
    referred to as pruning

46
Fig. 37 A trained brain (p. 116)
Implications regarding Stereotypical Behavior?
47
E O Wilson Sociobiology
  • Wilson originally studied ant colonies (and still
    does) (see, also p. 119)
  • Wilson postulated that much (all?) of behavior
    functions to increase copies of genes
  • Wilson explained much sexual and familial
    behavior, as well as altruism, in terms of his
    views of genetics (see, also, p. 110 back cover
    of book)
  • Wilson is controversial and many academics reject
    his ideas
  • Sociobiology was a predecessor to Evolutionary
    Psychology

48
Evolutionary Psychology (p. 107)
  • Evolutionary Psychology has exploded as a field
    in the last 15 years
  • Please read the book in this area (pp. 107-113)
  • Brain development in human ancestors appears to
    have exploded at a time period related to
    development of ballistic movement (Wargames)

49
Stepfathers v Natural Fathers (P. 109)
  • Many stepfathers do an excellent job of raising
    children
  • However, the probability of homicide
    (particularly due to beatings or other forms of
    discipline) is much higher with Step-Fathers
  • Homicide by natural fathers is often accompanied
    by suicide or uxoricide

50
Cultural Differences (p. 119)
  • Cultural differences abound and are topics of
    study for sociologists, anthropologists, and
    sometimes psychologists
  • One major area of study by psychologists
    regarding cultural differences involves personal
    space
  • For example, North Americans generally require
    more personal space than Latin Americans (p.
    120)

51
Studies indicate that
  • North Americans prefer more personal space than
    do Latin Americans
  • The French prefer more personal space than do the
    British
  • Arabs prefer more personal space than do
    Scandinavians
  • Women prefer more personal space than do men

52
Studies indicate that
  • North Americans prefer more personal space than
    do Latin Americans
  • The French prefer more personal space than do the
    British
  • Arabs prefer more personal space than do
    Scandinavians
  • Women prefer more personal space than do men

53
Cultural Differences (p. 119)
  • Book Kiss, Bow, or Shake Hands How to Do
    Business in Sixty Countries by Morrison,
    Conaway, Borden
  • Also Ed T Hall books

54
Edward T Hall
  • Many articles and books have been written on
    personal space, but the pioneer in this area was
    Edward T Hall
  • Edward T Hall wrote several important books
    related to cultural differences The Silent
    Language The Hidden Dimension and The Dance of
    Life

55
Ed Hall (contd)
  • Ed Halls work is more than academic major
    consumers of his work have been the State
    Department of the United States as well as
    multi-national corporations.
  • In addition to international differences,
    regional differences exist within the United
    States

56
Not mentioned in the book, the pioneer research
in the area of culture and personal space is
  • E O Wilson
  • Sherrington
  • Thorndike
  • Ed T Hall

57
Not mentioned in the book, the pioneer research
in the area of culture and personal space is
  • E O Wilson
  • Sherrington
  • Thorndike
  • Ed T Hall

58
Finis
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