Title: Top causes of death, US
1 Top causes of death, US Men Women Heart
disease Heart disease Cancer Cancer Stroke
Stroke Accidents (50 automobile) COPD COPD Pn
eumonia Pneumonia Diabetes (Types II) Diabetes
(Type II) Accidents (40 automobile) Suicide
Alzheimers disease Chronic liver disease Kidney
disease Homicide Septicemia Young men
(15-24) Young women (15-24) Accidents (60
automobile) Accidents (85 automobile) Homicide
Homicide Suicide Cancer
2Top causes of death Contributing factors Heart
disease Diet, smoking, exercise, stress (BP,
immune fx) Cancer Genes, environmental
exposures (smoking) Stroke Diet, smoking,
exercise, stress (BP) Accidents (mostly
automobile) Speeding, recklessness, seatbelt
use COPD Smoking, other environmental
exposures Pneumonia Vaccination, stress (immune
fx) Diabetes (Type II) Genes, diet, exercise,
stress (immune fx) Suicide Depression,
recklessness Alzheimers disease ? Diet, stress
(immune fx) Chronic liver disease Alcohol and
drug use Kidney disease (see Type II
diabetes) Homicide Hostility,
recklessness Septicemia Stress (immune fx)
3Fatty streaks concentration of LDL cholesterol
in the vessel walls that can . . . progress to .
. . Raised lesions formation of fibrin cap
over lesion including LDL cholesterol and
inflammation aka atherosclerosis, a major cause
of heart attack and stroke Other risk factors in
young adults hypertension, obesity, poor
glucose tolerance
McGill et al., Am J of Clinical Nutrition, 2000
4Friedman et al., J Personality Social Psychology,
1993
5Type A Personality
Type C Personality
easily aroused hostility sense of time
urgency intolerant of slow behavior competitive
achievement strivings work more, multi-task often
dissatisfied with output
passive acquiescent emotionally
repressed inhibited when stressed, depressed and
hopeless
depression dysregulates immune function,
increases risk for cancer
cynical hostility increases blood pressure,
risk of heart disease
depression increases risk of heart disease
hostility dysregulates immune function, increases
risk for cancer