Radiologic Findings in AIDS

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Radiologic Findings in AIDS

• Lipi Roy
• Class of 2008
• MD/MPH Candidate
• Radiology Elective Block III
• December 5th, 2007

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Symptoms Signs

• SYMPTOMS
• Fever, weight loss, night sweats
• Blurry vision, floaters
• Dysphagia, thrush
• Dyspnea, cough, CP
• Diarrhea, vomiting, abdominal pain
• HA, AMS, Dementia
• Depression, Suicide
• Skin lesions, rashes

• SIGNS
• Candidiasis (oral, esophageal)
• Oral hairy leukoplakia
• Meningismus (except in cryptococcus)
• Dry rales, consolidation
• Confusion, dementia, focal deficits
• Maculopapular rash, Kaposi sarcoma

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Pneumocystis carinii pneumonia (PCP)

• Normal CXR 6-23
• Bilateral interstitial infiltrates
• CT patchy ground-glass areas
• P.jirovecii
• Most common OI in HIV-infected patients
• Dyspnea, fever, nonproductive cough

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CNS Toxoplasmosis

• T1 weighted gadolinium-ehnanced sagittal MRI
• Thin-walled, hypodense, ring-enhancing lesions
• Edema
• Mid-line shift
• Multiple lesions 80
• Basal ganglia, gray-white junction parietal,
  frontal lobes, thalamus

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CNS Lymphoma

• T1-weighted MRI w/ gadolinium (L BG)
• Ring-enhancing lesion
• Surrounding edema
• Multiple lesions 50
• Can be 4cm
• Basal ganglia, deep white matter

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HIV Myelopathy

• T2-weighted MRI
• High-intensity lesion in C2-C5 posterior spinal
  cord
• During late-stage infection (LOW CD4 count)
• Assoc w/ AIDS dementia complex, peripheral
  neuropathies opportunistic CNS malignancies
  (lymphoma, PML)

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References

• www.emedicine.com
• www.learningradiology.com
• www.nature.com

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THANK YOU!