Clinical%20Decision%20Support%20and%20Knowledge%20Management

1
Clinical Decision Support and Knowledge
Management

• Staff
• Alan Rector
• email rector_at_cs.man.ac.uk or Alan.Rector_at_man.ac.u
  k
• Format
• Lecture demonstration, discussion, Web, and lab
• 1-2 lecture-demo sessions per week interspersed
  with lab work
• Assessment
• Web searches and summary on a given topic 20
• Continuous assessment lab projects 40
• Exam 40
• But you must pass the exam to pass the course!

2
Conferences

• Conferences
• MEDINFO 2004
• -triennial
• AMIA Fall Symposium (JAMIA)
• MIE Medical Informatics Europe
• AIME Artificial Intelligence in Medicine Europe
• Journals
• Journal of the American Medical Informatics
  Association (JAMIA)
• Journal of Biomedical Computing (Computers in
  Biomedical Research)
• Methods of information in Medicine
• International Journal of Biomedical Computing
• IEEE transactions on biomedical computing

3
Course Web Site

• Much of the course will use material from the web
• Part of your assessment will be to contribute to
  the web site
• Course Web Sitewww.cs.man.ac.uk/rector/modules/c
  ds
• (last years /cds-2003)
• Medinfo Ontology Tutorialhttp//www.cs.man.ac.uk/
  rector/tutorials/medinfo
• Bookmark the web site ASAP
• Look at the cds_links.htm file - it is also part
  of the handout.

4
Texts

• There just is no good single text
• Readings to be distributed
• Readings through web page
• Handbook of Medical Informatics
• See Web page Good General Sites and Books
• Official texts both badly out of date!
• Clinical Decision Support Systems Theory and
  Practice Ed Berner ES. Ball MJ1st Edition Jan
  1988, Springer Verlag ISBN0387985751
• Additional textEvaluation Methods in Medical
  Informatics Friedman CP, ed Wyatt JC, 1st
  Edition Jan 1987, Springer Verlag
  ISBN0387942289

5
Assessment details

• Web sites and review of a topic - Due Week 5 20
• Mini-project and Paper - Due final day of course
  40
• Something implemented in one of the tools
• Ideal is End to end - not likely possible
• Exam - 90 minutes written paper 40

6
Goals of Module

• Understand the context of medical decision
  support, guidelines and protocols
• Understand the difficulty of compiling protocols.
  (The task of gathering the evidence for
  protocols via systematic review requires a
  separate module.
• Understand some of the difficulties in
  translating guidelines for human interpretation
  into computable form
• Basic understanding of some of the technologies
  used
• Basic understanding of the foundations required

7
Technologies Tools

• Primary Technologies
• Structured text guidelines - Gemcutter
• New version expected in March currently
  sabotaged by Microsoft updates
• Knowledge Representation and Ontologies
  Protégé-OWL
• Rule based systems and Protocol Engines Tallis/
  ProForma / Protege
• Belief Nets Hugin or Netica (http//www.norsys.c
  om/)
• Object Oriented Design and UML - Universal
  Modelling Language - ArgoUML and HL7 RIM
• Supplementary technologies
• XML - the underlying syntax for just about
  everything these days
• XML related technologies - at least to know their
  names XSLT, RDF, etc.
• Best source is http//www.w3schools.com/ (not
  w3school (singular) which is a commercial
  squatter)

8
Fundamental Knowledge

• Bayes theorem and utility theory
• Enough to understand what makes good evidence and
  how evidence flows around a network
• The difference between probability and expected
  utility
• Elementary formal logic
• Enough to understand the underlying connections
  between Knowledge Representation, Rules Based
  Systems and Object Oriented Modelling
• Taught in half-hour a week mini-chunks plus
  problem sets

9
Plan for the Course

• Week 2
• Gemcutter (we hope)
• Week 3-6
• Knowledge Representation, Ontologies, Logic,
  Object Oriented Design, and UML
• Weeks 7-8
• Statistical Methods and Belief nets and Utility
• Weeks 9-10
• Formal Reasoning and ProForma (we hope)
• Week 11
• Review and catch up.

10
Feedback and Supplementary Material

• Up to you really
• Please email me suggestions to add to the course
  web site.
• rector_at_cs.man.ac.uk
• alan.rector_at_manchester.ac.uk