The Synapse

1
The Synapse

• What happens when neuron meets neuron?

2
Basic Neuropharmacology

• ACh
• Acetylcholine
• Acetyl CoA
• Acetyle Coenzyme A
• ChAT
• Choline
• Acetyltransferace
• AChE
• Acetylcholinesterase

3
Basic Neuropharmacology

• ACh
• Acetylcholine

4
Basic Neuropharmacology

• Direct Agonists and Antagonists

5
Basic Neuropharmacology

• Indirect Agonists and Antagonists

6
Basic Neuropharmacology

• NMDA Receptor

7
Basic Neuropharmacology

• NMDA Receptor

8
Basic Neuropharmacology
9
Drug Mechanisms

• Dopamine
• Parkinsons
• Disease
• Schizophrenia
• Stimulants
• Cocaine
• Amphetamine

10
Drug Mechanisms

• Dopamine
• Stimulants
• Cocaine
• Amphetamine
• Norepinephrine
• (NE) is a transmitter
• in the sympathetic nervous system

11
Drug Mechanisms

• Dopamine
• Parkinsons
• Disease

12
Drug Mechanisms

• Dopamine
• Parkinsons
• Disease

13
Drug Mechanisms

• Dopamine
• Schizophrenia
• Dopamine
• Hypothesis
• Drug Treatments block the D2 receptor

14
Drug Treatments