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1Clinical and Translational Science Awards
(CTSA)
A Centerpiece of the National Institutes of
Healths Roadmap Initiatives
2What Prompted the CTSA Initiative?
U.S. Healthcare Outcomes
- Despite large expenditures for research and the
provision of health care services - Only 55 of Americans receive evidence-based or
recommended processes in their health care. - The US health care system actually exposes
patients to unnecessary harm. - There is a lack of coordination of care for
patients seen by multiple physicians and care
providers. - Only 53 of adult patients report that their
physician typically informs them about treatment
choices.
3More Healthcare Outcomes
- The US spends 15 of the GDP on health, whereas
the average among industrialized nations is
8.5. - Still, 16 of the US population remains uninsured
and is at risk for receiving no or inadequate
health care services. - Large expenditures do not translate into better
health outcomes. - The US is at the lower end of the spectrum among
industrialized nations for a number of health
care metrics.
4Despite These Expenditures Congress and the
Public Want to Know Why We Arent Doing Better
5A New Research Paradigm
- NIH recognized that current approaches for
bringing new scientific discoveries to bear on
the nations health are uncoordinated,
inefficient, wasteful and sometimes
counterproductive. - NIH developed the Roadmap Initiative to guide the
changes necessary to build an integrated system
that is more effective than current approaches. - NIH sees the Clinical and Translational Science
Awards (CTSA) as one key element in the
accomplishment of its goals.
6Understanding the Basics
Clinical and Translational Research
From Bench (Biomedical and Behavioral Science
Research)
To Bedside - Clinical Trials (Best Practices)
To Community (Improved Health)
7UTHSCSA What is our Goal?
- To create an academic home that will facilitate
the translation of biomedical research from bench
to bedside to the community and result in better
health outcomes for South Texas
Institute for Integration of Medicine and
Science A Partnership to Improve Health
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9IIMS/CTSA Partners
- CTSA Partners
- Christus Santa Rosa Childrens Hospital
- San Antonio Metropolitan Health District
- San Antonio Military Medical Center
- South Texas Veterans Health Care System
- Southwest Foundation for Biomedical Research
- University Health System
- Other University of Texas Schools
- UT Brownsville
- UT Pan American
- UT San Antonio
- UT School of Public Health Regional Campus
Institute for Integration of Medicine and
Science UTHSCSA and Regional Academic Health
Center Lead organization
10Timeline
- UTHSCSA planning grant submitted March 2006
- Funded September 2006 to September 2007
- Budget 150K
- Full CTSA proposal submitted January 17, 2007
- Priority score 176
- Rank 16 of 31
- Funding through 12
- Revised resubmission under new RFA
- Submitted November 7, 2007
- Major criticisms
- Complex organization with multiple highly diverse
partners - Biomedical informatics
- Review and funding cycle
- Initial review group February 5-6, 2008
- Score available in mid to late February
- Written critiques April 15, 2008
- NCRR National Council May 15, 2008
- Earliest funding date July 1, 2008
11CHART Center
(Childrens Health Advocacy Research and
Treatment Center)
Mission To provide a child friendly environment
conducive to pediatric research.
12Where
- 6,000 ft2
- 3 private exams rooms
- 4 cubicle beds
- Consultation room
- Sample processing lab
- Specimen storage (-80o)
- Research Pharmacy
- Coordinator workspace
- Study monitor work area
- Regulatory document space
13Who
- Jannine Cody, PhD
- Administrative Director
- Daniel Hale, MD
- Medical Director
- Robin Tragus, RN, MSN
- Research Operations Manager
- Kathleen Cobb, RN
- Research Nurse
14Who
- Anyone interested in childrens research
- UTHSCSA faculty
- Community Investigators
- Physicians
- Therapists
- Psychologists
- Educators
15What
Facilitate research for investigators
- Surveys / interviews
- Blood / urine collection
- lab sample processing
- Specimen storage (-80o)
- Physical exam space
- Infusions
- Coordinator assistance
- Coordinator work/office space
16What
Facilitate research for investigators
- Institutional approvals / Compliance
- IRB
- SR / GCRC Utilization review
- Budget preparation
- COP / OGM process advice
17What
Facilitate research for investigators
- Financial tracking
- Billing for procedures
- Patient incentives
- Income
18What
Facilitate research for investigators
- Talk to us about your ideas and needs
704-4447 or tragus_at_uthscsa.edu
19What
Facilitate research for investigators
- What we dont do
- Grant writing (content)
- Recruit patients
- Write manuscripts
- Physician procedures