Glucose Transport

1
Glucose Transport

• Ben Baker
• Heidi Erchinger
• Julia Sivakova
• Chandler Keck

2

• Speculate how intercellular movement is
  accomplished with GLUT4 transporters and why they
  exist.

3
Introduction

• Cells need energy which they get in the form of
  ATP. The fuel for ATP production is glucose.
• The role of insulin is to signal the cells that
  excess glucose is available
• Facilitated Diffusion

4
GLUT4
5
Insulin Dependent
6
Insulin Independent

• Insulin free
• Fast response facilitated diffusion
• Fight or Flight
• Prime suspect is Calcium

7
Diabetes

• Characterized by
• Inadequate insulin secretion from beta cells in
  the pancreas
• Reduce insulin receptor effectiveness

• How can a diabetic get enough glucose into their
  muscle cells?
• Exercise to recruit GLUT4