Principles of industrial fermentation

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Principles of industrial fermentation
FAS Center for Systems Biology Harvard University
Chris Brown, Marcelo Vinces Kevin Verstrepen
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A cell
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A cell
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20 amino acids
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Peptide bond
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Proteins
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Proteins, prosthetic groups
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Alpha helix
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Beta sheets
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Carbohydrates / sugars
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Carbohydrates Fischer and Haworth projection
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Enantiomers, chirality
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Carbohydrates
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Starch
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Carbohydrates
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Lipids
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UFAs
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Sterols
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Sterol biosynthesis
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Lipids
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Nucleic acids
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Nucleic acids
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A gene
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Malt yeast food

• Nutrition for cells
• C,H,O,N,S,P
• Na, Ca, Mg, K, Fe
• Zn, Cu, Co, Mn, Mo, Se, Ni
• Vitamins
• O2
• Carbon/organic molecules Prototroph (
  autotroph) Auxotroph
• Energy Phototroph, Chemotroph, Litotroph,
  Organotroph

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Some DNA facts

• Genome
• All cells have DNA?
• AT-content
• How much DNA?
• How many genes? How much coding DNA in a
  genome?
• Polymorphisms

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Fermentation
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Student seminars
FAS Center for Systems Biology Harvard University
Chris Brown, Marcelo Vinces Kevin Verstrepen
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Subjects

• Wine (2 3)
• Distilled
• Bioethanol
• Biodiesel / Biofuels / alternative energy
  sources
• Cheese, Yoghurt, vinegar
• Bread
• Wastewater
• Heterologous substances
• Medical aspects
• Law / marketing / history
• Business / globalization

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Evaluation

• A. Specific content (if not relevant, write
  N/A)
• What is the starting raw material for this
  process?
• What microorganisms are involved?
• What is the source of carbon?
• What is a major difference between this
  fermentation process and beer fermentation?
• Where (what countries or regions) is the product
  mainly produced?
• What, in your opinion, are the two most
  important/interesting conclusions/aspects of this
  presentation? Why?
• B. Organization
• Was the seminar well structured? Any
  suggestions?
• Was the topic / new aspects introduced
  appropriately?
• Was the topic put into a larger context (e.g.
  relation to beer brewing or any other process)
• C. Delivery
• Comments on public speaking (engagement of
  audience, pace, gestures, facial expression,
  pitch, volume, tics)
• Use of powerpoint/ visual media

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PubMed
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Google scholar
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SGD