Design and development of soft nanomaterials from biobased amphiphiles

1
Design and development of soft nanomaterials from
biobased amphiphiles

• George John and Praveen Kumar Vemula
• The Royal Society of Chemistry 2006
• Soft Matter, 2006, 2, 909914

??????Q26961040???
2
Introduction

• Design and development of different forms of soft
  matter from renewable (biomass) feedstocks is
  gaining attention in current research.
• Cashew nut shell liquid, an industrial
  by-product, was used as a raw material to
  synthesize aryl glycolipids which upon
  self-assembly generated an array of soft
  materials( lipid nanotube,twisted nanofibers)
• amygdalin, a by-product of the apricot industry,
  was used to develop novel amphiphiles, which
  showed unprecedented gelation properties in a
  wide range of solvents.

3
Soft nanomaterials from cashew nut shell liquid
(CNSL)(cardanol,cardol) helical/twisted fibers,
lipid nanotubes, gels and liquid crystals
4
(No Transcript)
5
(No Transcript)
6
Soft materials from amygdalin biocatalysis as a
tool to make and break hydrogels
7
SEM images of a) morphology of a hydrogel formed
from AMG3 and b) morphology of an organogel
formed from AMG1.
8
Enzyme triggered drug delivery
c) drug (curcumin) encapsulated hydrogel, d) gel
with enzyme solution immediately after addition
and e) after 12 h. Crystal structure of AMG1 in
water f), the extended hydrogen bonding network
can be viewed.
9
Conclusion and outlook

• Upon utilizing basic self-assembly properties of
• glycolipids, a wide range of soft materials such
  as
• lipid nanotubes, helical/ twisted nanofibers,
  low-
• molecular-weight hydro/organogels and liquid
• crystals were generated such materials would
  find
• applications in various fields such as
  biomaterials,
• templated synthesis and biosensors.