Oxygenase PowerPoint PPT Presentations

Microsomal Heme Oxygenase System

Bacterial aromatic-ring dioxygenase is a normally three-component enzyme system, ... expression system was also able to oxidize benzoate, m-toluate, or 1-hydroxy-2 ...

J Biol Chem 269:25049-25056. 2. Alam J, et al. 1994. J Biol Chem 269:1001-1009. 3. Lee PJ, et al. 1996. Am J Respir Cell Mol Biol 14:556-568.

Lung macrophages induce HO-1 after hemin induction (1) ... Co-induced ferritin sequesters heme iron released from the reaction (2) but...

Prostaglandins, cyclo-oxygenase and the GIT HPETE PGH Eicosanoids Linoleic acid (diet) Leukotriene synthesis Arachidonic acid Prostaglandin synthesis Arachidonic acid ...

a Unique Antiplatelet Agent. COX (cyclo-oxygenase) ADP (adenosine diphosphate) ... Patients with ASA intolerance were excluded ...

Neurotransmitters Diffusible Gases Nitric Oxide (NO) Carbon Monoxide (CO) Heme CO + biliverdin Heme Oxygenase Arginine NO + Citrulline Nitric Oxide Synthase (NOS ...

Figure 24-36 Probable mechanism of the oxygenase reaction catalyzed by RuBP ... Figure 25-2 Catalytic action of phospholipase A2. Page 911 ...

Ibuprofen generally blocks a certain substance within the body known as cyclo-oxygenase (COX).This substances is mixed up in the output of several chemical substances within the body, most of which are identified as prostaglandins.

Painkillеrs, or analgеsics, arе medications crafted to relieve pain and discomfort stеmming from various conditions likе injuriеs, surgеriеs, chronic illnеssеs, inflammatory disordеrs and period cramps. Meftal Spas, an anti-inflammatory painkiller & muscle relaxant, is widely used by women to get symptomatic relief from period cramps and menstrual discomfort. Meftal is mainly a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). It provides instant relief by blocking the effect of a chemical messenger, cyclo-oxygenase (COX) enzymes, which leads to a reduced sensation of pain.

FAD. FMN. BH4. Calmodulin. Ca2 . Reductase. Oxygenase. NOS domains. Catalytic site of human iNOS ... FAD NADPH. FMN. NH2. COOH. CaM. Zn. Zn. Zn. Myr. Palm ...

1) the details of redox relationships, free-energy changes during e-transport, ... Calvin / Bensen cycle -- RUBP carboxylase oxygenase (Rubisco) Photorespiration ...

The Dumont-UCLA Transplant Center, and Division. of Cardiology, David ... Interleukin-10 induces expression of heme oxygenase-1 (HO-1) with potential anti ...

Sesi n Bibliogr fica 2208. Los COX-2, en tratamientos prolongados, son ... gastrointestinal outcomes in patients taking cyclo-oxygenase-2 inhibitors or ...

Title: Chapter 15 (part 2) Author: David Shintani Last modified by: DShintinai Created Date: 3/26/2002 2:50:11 PM Document presentation format: On-screen Show (4:3)

Reduced thioredoxin can activate enzymes by reducing disulfides in regulatory domains.

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Melvin Calvin at Berkeley in 1945 showed that Chlorella could take up 14CO2 and ... 4 of five carbons from R 1,5-BP salvaged. Loose one carbon as CO2 ...

By tracking radioactive C in CO2 through. time as it reacted with chloroplasts in algae. ... 3-PGA (a 3 carbon compound) Chloroplasts. Photosynthesis is basically the ...

Title: PowerPoint Author: kubs Last modified by: Tianluo Created Date: 9/7/1998 1:31:14 AM Document presentation format: (4:3)

A straight forward presentation about C3 cycle its very simple and useful

Three isoforms of nitric oxide synthase (NOS) have been identified. ... NOS catalyzes the conversion of arginine to citrulline and nitric oxide (NO) ...

20. Photosynthesis: carbon fixation by the C3 and C4 pathways ... Stoichiometry of CO2 assimilation in the Calvin cycle. CO2 H2O. 3. 3-phosphoglycerate ...

... PGs Salicylates aspirin acetylsalicylic acid ...

Bacteria have the natural ability to either grow on toxic ... glyoxylate formate. glyoxylate formate. TCE epoxide. chloral hydrate (not in whole cells) ...

Elucidated by Melvin Calvin after WWII. 1961 Nobel Prize. Tech Alum! ( 31) How does this happen? Molecular activation of RuBisCO by CO2 involves the formation of a ...

The Biochemistry of Jaundice A collaborative effort of Group 3 Section 1C2 Members: Animations by: Gerald Fuentes Formation of Bilirubin Bilirubin Metabolism ...

2H2O 4e- 4H O2 -ATP synthesis (ADP Pi ATP) -reduction ... The Calvin Cycle C-fixation reactions * Rubisco. Photorespiration : The problem with Rubisco: ...

Enzymes and chlorophyll are. imbedded in the thylakoid membranes ... 1. Chlorophyll fluorescence. 2. Heat (= 'non photochemical quenching' ...

Some plants have an alternative pathway where CO2 is first fixed ... C3 and C4 metabolism are separated in time (same cell=mesophyl) e.g. pineapple (CAM cycle) ...

Pharmacology 4. Control of Inflammation. NSAIDs. Chemical Mediators of Inflammation ... arachidonic acid metabolites ie prostaglandins, leukotrienes and lipoxins ...

The infection process during nodule organogenesis occur simultaneously Plant: attractants Rhizobia: Nod factors Fuse with the membrane of root cell

Biochemistry

6. Photosynthesis: carbon fixation by the C3 and C4 pathways ... Stoichiometry of CO2 assimilation in the Calvin cycle. CO2 H2O. 3. 3-phosphoglycerate ...

From Biosphere to Molecule

Biodegradation of Xenobiotic Compounds Xenobiotics : compound have been produced artificially by chemical synthesis for industrial or agricultural purposes e.g ...

Ischemia-Reperfusion-induced Lung Injury Am J Respir Crit Care Med,2003 ... Iron Release. Essential element, highly toxic under pathophysiologic or stress conditions ...

Title: Metal Ions in Biological Systems Author: jirka Last modified by: JIRKA KOZELKA Created Date: 10/31/2005 4:21:31 PM Document presentation format

As these receptors, which may be regarded as lateral chains of the protoplasm ... become occupied by the toxin, the relevant normal function of this group is ...

Metabolism of Chemicals

Tebo, B. M., Bargar, J. R., Clement, B. G., Dick, G. J., Murray, K. J., Parker, ... Trouwborst, R. E., Clement, B. G., Tebo, B. M., Glazer, B. T. & Luther, G. W. ...

Figure 24-17 Schematic representation of the thylakoid membrane showing the ... Lipid Metabolism. Suggested problems: 1, 4, 5, 6, 8, 9 ...

Table 24-1 Standard and Physiological Free Energy Changes for the Reactions of the Calvin Cycle. ... PS SONG. http://www.csulb.edu/~cohlberg/Songs/photosynthesis.mp3 ' ...

... (continued) Chlorophyll structures. Page ... the electronic states of chlorophyll and their most important ... is trapped by the RC chlorophyll. Page 877 ...

The capture and conversion of solar energy to chemical bond energy ... Photolysis replaces electrons removed from chlorophyll. Fig. 4-10 ...

BIOCHEMISTRY

Topics: Regulation of the Calvin Cycle Photorespiration CO2 concentrating mechanisms Sucrose and starch synthesis Balance: Starch vs Sucrose Synthesis Many of the ...

Ac tylcholine est rase (cible mol culaire des insecticides organophosphor s) ... Hom ostasie des prot ines. Chaperones. Assemblage. Trafic transmembranaire et s cr tion ...

chemical energy used to convert water and CO2 into sugars, O2 is ... Facultative CAM plants. C3 when not stressed. CAM under stress. due to gene expression ...

Determination of Sites of CYP1B1 Mutations in Aligned Sequences of Cytochrome ... most sites are well conserved e.g. hydrophobicity, hydrophilicity as shown here. ...

To characterize the expression of ribulose 1-5 bisphosphate carboxylase ... Cell Lysis. Cells harvested (1 gm) Cell lysis accomplished via grinding in liquid nitrogen ...

Biosynthesis of carbohydrate polymers Starch in plants, glycogen in vertebrates These polymerization reactions utilize sugar nucleotides as activated substrates

... (Common increases in Tf cassettes): - Myosin regulation - Mitochondrial genes ... DIFFERENCES (Oppositely directed Tf cassettes): - PDH (synthesis of components) ...

... likely to develop asthma if someone in your family has it. You can 'catch' asthma from someone else who ... Someone with asthma can provoke episodes anytime. ...

Alan Brash, Dept of Pharmacology, RRB 510. Furchgott's results. reductase domain ... Nitric Oxide Synthase (NOS) are fusion proteins with ...

Vinyl Chloride. Vinyl chloride. Known carcinogen. Damages the liver, lung, kidneys and heart ... Vinyl Chloride (mutagen & carcinogen) Problem ...