Serologic markers measured in immunogenicity trials ... www.lsumc.edu/campus/micr/opson.htm. Without Ab and C' Pnc are not being. engulfed. With Ab and C' ...
Complement functions Host benefit: opsonization to enhance phagocytosis phagocyte attraction and activation lysis of bacteria and infected cells regulation of ...
Lysis of cells/ bacteria and viruses. Opsonization for phagocytes. Immune Clearance ... Lysis of 'innocent' neighbour cells. Red blood cells. Activation of ...
Removal of Ig-coated organisms (opsonization) or cells (ADCC) ... Hydrogen peroxide. Heightened microbicidal state. IFN- induces expression of FcR on M ...
Opsonization and enhanced phagocytosis of the bacteria. Bacteria that express mannose on their surface may bind mannose ... Agglutinate viruses. IgA Antibodies ...
Definition a plasma protein of hepatic origin, part of the innate immune ... Targets microbial pathogens for destruction via opsonization, enhancement of ...
Innate vs. Acquired (adaptive) immunity. Acquired = antigen and antibodies ... Activation of complement for lysis, inflammation, opsonization. Complement System ...
Same amount of antibody in each tube. Amount of precipitation. antibody excess ... ELISA Microtiter Plate. http://virology-online.com/presentations/Tests.htm ...
BACTERIA CAUSE DISEASE BY SECRETING TOXINS. High Affinity IgG and IgA Can Neutralize Toxins ... Ig Can Block Adherence of Bacteria. IgA at mucosal surfaces. IgG ...
Humoral Immunity and Complement Robert Beatty MCB150 Humoral Immunity Transfer of non-cell components of blood-- antibodies, complement Humoral immunity = antibody ...
Product Biological Effects Regulation Biological properties of C-activation products anaphylactic as C3, but much more potent; attracts & activates PMN causes ...
2. Describe neutrophil function in terms of the three phases of phagocytosis ... Deranged Neuts! 1. Abnormal adhesion. 2. Impaired chemotaxis. lazy leukocyte syndrome ...
Antigen-Antibody Reactions Antigen-antibody interactions: Are reversible specific non-covalent biochemical reactions: Hydrogen bonds (A chemical bond in which a ...
Complement Dr. Mona Badr Assistant Professor King Saud University Thank you Complement The Complement System Consists of : Approximately 30 soluble and cell-bound ...
Nucleated cells are harder to lyse. Not particularly effective against tumor cells ... (can't lyse bacteria but seem to control. infections) Early components of ...
Host Defense Mechanisms (non-specific) BIO162 Microbiology for Allied Health Chapter 15 Page Baluch Host Defenses Resistance Ability to ward off disease Varies among ...
Immune system J. Ochotn The main functions of the immune system Immune system belongs to the basic homeostatic mechanisms Defense - identification and protection ...
some antiserum was first incubated with. ovalbumin and then electrophoresed; ... Monomer in serum, multimer elsewhere. helps protect portals of entry in body ...
Title: Complement Author: Abdul Ghaffar Last modified by: acadpm01 Created Date: 8/10/1998 2:23:48 PM Document presentation format: On-screen Show (4:3)
Monoclonal Abs bind specifically to a single site (epitope) on a ... (Medarex, Abgenix, Kirin) Breedveld, Lancet 2000 355:9205. 18. 26.02.2004. Antineoplastic ...
Title: The Acute Phase Response Author: Joe Schmoe Last modified by: garwinS Created Date: 8/15/1999 1:46:00 PM Document presentation format: On-screen Show
Different materials preferentially adsorb different proteins, or none at all (non-fouling) ... Presence of bioactive molecules (bacterial cell wall, tissue ...
Lecture 1 Introduction to the Principles of Immunity Innate vs. Acquired Immunity- conceptual and practical difference The vertebrate invention of acquired immunity
Refers to various PHYSICAL, CHEMICAL, and CELLULAR attributes that collectively ... Neutrophils. Macrophages. Phagocytosis of Bacteria by Macrophages. Phagocytosis ...
Hypersensitivity ( ) Jianzhong Chen Institute of Immunology Zhejiang University School Of Medicine chenjianzhong@zju.edu.cn Type II hypersensitivity ...
Immunoglobulins Biological Properties This mechanism can be used in patients who are sick of tetanus or diphtheria. * * Passive immunity can be natural (like mother ...
... (ITAM), activating receptor -KLR(killer lectin-like receptor): Heterodimer of CD94 & NKG2 (C type lectin) CD94: short cytoplastic region, no signal ...
Immunology: Specific Immunity Immunity: not being susceptible to disease Types of immunity Innate: you have it from birth. Species: as humans, immune to diseases of ...
Immunology (elective) MLIM-101 Prepared by: Dr. Mohamed S. Abdel-Latif Learning Outcome: At this time you should know the following: 1. To compare and contrast ...
Defense against pathogens, possibilities of therapeutic affecting of the immune system Martin Li ka Extracellular microorganisms Typically bacteria or parasites For ...
Title: PowerPoint Presentation Last modified by: User Created Date: 1/1/1601 12:00:00 AM Document presentation format: On-screen Show (4:3) Other titles
C3a/4a receptor is expressed by phagocytes, endothelial. cells ... phagocyte. C1qR. Phagocyte recognizes C1q deposited on the surface of apoptotic cell ...
Monoclonal Antibodies (mAbs) Antibodies (Abs). Also known as immunoglobulins (Ig). Comprised of 2 heavy chains and 2 light chains Monoclonal Abs bind specifically to ...