Genasense PowerPoint PPT Presentations
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CR and nPR Require Normalization. of All Disease Parameters (2 Months ... CR/nPR Significantly More Durable with Genasense/FC. From Date of Initial Response ...
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Temozolomide (TMZ) ... versus TMZ p.o. each 4 weeks. Primary Endpoint Survival (superiority) from median 6 mo-DTIC to 9 mo-TMZ ...
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... Flu/Cy ... both arms, received same chemotherapy (Flu/Cy) Fludarabine 25 mg/m2/day ... prior to treatment with Flu/Cy. Central venous access catheter ...
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... 1(Bryostatin 1) UCN-01 (Velcade , bortezomib) (Genasense) (Flavopiridol) D1, ...
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... (Genasense ) : oligonucle tido antisentido frente a Bcl-2 Fase II Docetaxel-oblimersen RR similar docetaxel Fase II randomizado Docetaxel con /sin ...
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Bcl2 is Expressed in CLL Patients
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Title: MANAGEMENT OF THE OLDER PATIENT WITH ACUTE MYELOID LEUKEMIA Author: MTallman Last modified by: Created Date: 4/9/2005 6:33:49 PM Document presentation ...
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Phase 1 Design: Optimum Biologic Dose. Tissue acquisition ... Optimum biologic dose may differ between adult and pediatric tumors. Pre-clinical data required ...
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Title: Apresenta o do PowerPoint Author: Rodrigo Sampaio Leite Last modified by: Sector Pharma Created Date: 9/17/2001 5:14:49 PM Document presentation format
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... 7% of Human Cancers Response Rates & B-RAF Mutation Status Sorafenib Sorafenib Spectrum vs. Whole Kinome Single-agent Sorafenib in Melanoma 39 patients with ...
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Title: 1 Author: Last modified by: colin Created Date: 9/15/2004 7:08:45 AM Document presentation format: On-screen Show (4:3)
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Advances in Biology and Pathophysiology of Multiple Myeloma Amer G. Rassam, MD Apoptotic Signaling Pathways Velcade ZME-2 Dex ImiDs, Velcade HDAC-I, 2ME-2 TNF FasL ...
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Acute Myeloid Leukemia. Peter M. Voorhees, M.D. The University of North Carolina at Chapel Hill ... A receptor tyrosine kinase expressed in 70 100% of AML cases. ...
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Macro view of the Pharma Industry. Impact of Licensing / BD. How it's Done ... Company. Sales ($B) Shr. LC. Major Therapy Areas. PFIZER. 45.0. 10.4. 9. CV 37 ...
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Trattamento medico del melanoma recidivato o metastatico Stefano Pepe Dipartimento di Endocrinologia ed Oncologia Molecolare e Clinica Universit Federico II - Napoli
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Lack activity against LDH (more selective) Lack aldehydes (non-reactive) ... are highly selective for BIR2 vs. BIR3 ... Selectivity profile under evaluation ...
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TRAnslational research in Clinical Oncology (TRACO) * * * * * * * * In chronic myelogenous leukemia, a translocation occurs between chromosomes 9 and 22.
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Oncology Products. Division of Medical. Imaging and. Hematology Products. 4 ... Includes drugs/biologics reviewed in Office of Oncology Drug Products ...
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Tumor vaccines to prime the host immune system against host tumor ... Ordered dismantling of cell structure. Mitochondrial outer membrane permeabilization ...
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racemization and acid labile: Asp. disulfide exchange: Cys, disulfide ... Mutate chemically labile amino acids to other amino acids, however, antigenicity ...
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TRAnslational research in Clinical Oncology (TRACO) * * * * * In chronic myelogenous leukemia, a translocation occurs between chromosomes 9 and 22.
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APOPTOSIS Apo: Greek: from, away Ptosis: Greek: fall, falling A specific type of cell death first described in 1972 by Kerr, et al in the British Journal of Cancer
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Most often has the form of a 'double helix', which consists of two paired DNA ... Malfunctioning proteins are implicated in a number of diseases. Regulation. Structure ...
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Patients use clinical trials to survive. Access to the latest drugs ... Clinical trials move GIST research forward ... FDA approved for advanced kidney cancer ...
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