Drug Interactions Of Pioglitazone PowerPoint PPT Presentations

Pharmacodynamic Drug Interactions Mary Lynn McPherson, Pharm.D., BCPS Professor, University of Maryland School of Pharmacy mmcphers@rx.umaryland.edu

Drug interactions of Incretin mimetics (Exenatide) with other drugs like Warfarin, Digoxin, Paracetamol, Antibacterials, Thyroid hormones, Danazol and ACE inhibitors are dealt in this presentation. The interactions of Amylin analogue (Pramlintide) with other drugs such as Alpha glucosidase inhibitors, Danazol, ACE inhibitors, Thyroid hormones, Paracetamol and Antimuscarinics are also dealt in this presentation.

Diabetic patients take Insulin and/or other oral hypoglycemic and antihyperglycemic drugs to control their blood sugar levels. Along with antidiabetic medicines they may take drugs such as OTC medicines, prescription medicines, etc.to treat other illnesses which may interact with them. Drug interactions of Insulin with other drugs like Fluoroquinolones, Betablockers, Aspirin, Thiazolidinediones, Antipsychotics, Androgens, Antimalarials and Orlistat are dealt in this presentation. The interactions of Insulin with Complementary and alternative medicines (CAM) such as Bitter melon, Ginkgo, Ginseng, Gymnema, Licorice and Fenugreek with smoking and with alcohol are also dealt in this presentation.

Pharmacodynamic Drug Interactions Mary Lynn McPherson, Pharm.D., BCPS Professor, University of Maryland School of Pharmacy mmcphers@rx.umaryland.edu

Title: (Antidiabetis Drugs Insulin and Oral Antisiabetis Drugs) Author: Last modified by

Antidiabetis Drugs Insulin and Oral Antisiabetis Drugs Department of Pharmacology, Peking Union Medical College Caiying Ye Overview diabetes mellitus A chronic ...

Thiazolidinediones interact with Abiraterone, Pixantrone, Azole Antifungals, Fibrates, Teriflunomide, Dabrafenib and Rifampin. Pioglitazone also interacts with Calcium channel blockers (Nifedipine, Amlodipine), Cobicistat, Piperaquine, Ifosfamide, Tolvaptan, Midazolam, Tipranavir/Ritonavir, Macrolide antibiotics, Sulphonamides, Amiodarone, Topiramate, Oral contraceptives, Atorvastatin, Danazol and Trandolapril.

Title: Pharmacology Author: zcy Last modified by * Created Date: 8/24/2002 2:50:00 AM Document presentation format: Company

Part 2 Thyroid hormones and antithyroid drugs

Drug Safety in Chronic Kidney Disease Primary Care Clinician Conference 4/26/14 Michael J Choi, MD Johns Hopkins University School of Medicine mchoi3@jhmi.edu

Title: Acute Renal Failure Author: Johns hopkins Last modified by: Jessica Joseph Created Date: 7/30/2002 12:40:54 AM Document presentation format

Acts at GPCR in the liver to facilitate gluconeogenesis and mobilization of glycogen stores ... induce insulin secretion, decrease in gluconeogenesis ...

Thyroid hormones and antithyroid drugs Dept of Pharmacology Shi-Hong Zhang ( ) shzhang713@zju.edu.cn Thyroid hormones Hyperthyroidism Hypothyroidism cretinism ...

PHARMACOLOGY 1391 Studies the effects of drugs and how they exert their effects. acetylsalicylic acid (ASA) reduce inflammation, pain and fever inhibit the action of ...

66 year old full professor at WFU comes in and states she ... Other meds include Ditropan, Diazepam, Tramadol, Cyclobenzaprine, Aspirin and Lisinopril. ...

Incidence of Urinary Bladder Proliferative Lesions in Male Rats ... No urinary bladder cytotoxic, proliferative, or inflammatory changes in monkeys after 1 year ...

Dr. Ranjit Jagtap Daughter says Chemotherapy drugs, such as doxorubicin, can damage the heart muscle and lead to heart failure. This is because these drugs can cause oxidative stress, inflammation, and other changes in the heart that can impair its ability to pump blood effectively.

'As older patients move through time, often from physician to physician, they are ... tramadol. aspirin. pioglitazone. NSAID. atenolol. glyburide. Case B ...

Avandia (rosiglitazone maleate) GlaxoSmithKline NDA 21-071 Supplement 022 FDA META-ANALYSIS Joint Meeting of Metabolic & Endocrine Advisory Committee and Drug ...

Identify uses and varying actions of these drugs. ... with type II diabetes if diet and exercise can't control blood glucose levels. ...

When to Spare Some Pharmaceutical Care Jovino Hernandez PharmD Clinical Manager Winter Haven Hospital Pharmacy Services Potentially Inappropriate Due to Drug ...

Learn the horrible effects your diabetes medicine have on your health and also know the secret to avoid the medicines and take controll of your life.

Medical Conditions and Medications Impacting on Falls, Injury and Capacity to Exercise With thanks to Dr Rob Morris

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High prevalence of sleep disordered breathing -do you snore? -do fall asleep during the day? ... Serum creatinine 133 mol/l or Creatinine clearance 60mls/min ...

Neurology References Physician s Desk Reference (PDR) White pages manufacturer index of products Pink pages product names by trade name Blue pages products by ...

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Based on 2 open-label trials, ... In other words, what percent of new users of each class (reading down), ... Probably closest to capturing true new diabetics ...

BVS 611 Slide Deck II BVS 611 Pharmacology I Important notation for individuals taking medications for treatment of hypertension: Taking frequent or routine doses ...

Biguanides are derivatives of the antimalarial agent Chloroguanide. ... Type 2 diabetes failed on diet ... Improves postprandial glycemia ...

Sulfonylureas : stimulate cells to produce more insulin. 1st generation (1)Orinase (tolbutamide) (3)Tolinase (tolazamide) (6)Diabinese (chlorpropamide)

Should statins be given to all diabetic patients ? AGAINST THE MOTION Dr Bharti Kalra Bharti Hospital Karnal Haryana NO NO NO NO Safety profile was good However ...

Title: DIABETES Author: dboles Last modified by: Cory True Created Date: 4/24/2006 11:38:09 AM Document presentation format: On-screen Show (4:3) Company

Type 2 Diabetes Mellitus. Most common type ... Type 2 diabetes. Metabolic syndrome. The ... Are strongly associated with the development of type 2 diabetes. ...

Pharmacology of Hormones Endocrine Pancreas Martin Sterba, PharmD.,PhD. Dept. of Pharmacology Glucagon Polypeptide hormone (29AA) Secreted by pancreatic -cells ...

PHARMACOLOGIE DES ANTIDIABETIQUES ORAUX CHEZ LE SUJET AGE Actualit s et perspectives C. Bruhat1,2, B. Diquet2, G. Berrut1 1 G rontologie clinique, 2 ...

has anorectic effect. low risk of hypoglycemia. don't lead to weight gain ... central anorectic effec. 2. Orlistat. inhibitor of intestine lipase. less ...

Review medical therapies for type 2 DM. List important considerations in ... Slow absorption of carbohydrates and reduces rise in postprandial glucose levels ...

University of California, San Francisco-San Francisco General Hospital ... Side effects: flatulence, diarrhea, abdominal cramps, decreased metformin absorption ...

Age (men 55, women 65) Family History of premature CVD (men 55 or women 65) ... Kaplan-Meier curves for all-cause and cardiovascular deaths with no blood ...

Frequency of diagnosed and undiagnosed diabetes and IGT, by age (U.S. data - Harris) ... Seattle Defibrillator Experience. GREACE Study. www.diabetesclinic.ca ...

Network Clinical Research Units- CRU- : 29 CRUs WW ... B. BOCK. OPERATIONS & Regional Monitoring. CVS/THR. M. GROSSO. INM/MAD/RSP. O. ABDULLAH ...

R.A.Howland, M.J.Mycek: Lippincott's Illustrated Reviews: Pharmacology,3rd ed. ... The inner (zona reticularis) - adrenal androgens (e.g., dehydroepiandrosterone) ...

4. Describe the metabolic effects of insulin and the major ... 2. Understand the physiology of circulating insulin, C-peptide and proinsulin. ...

Title: Diabetes Detection and Care and Study Demonstration Project Author: Anthony Cavallerano Last modified by: papagni Created Date

Symptoms (polyuria, polydipsia, unexplained weight loss) plus casual ... Side effects: weight gain, pedal edema. Caution: CHF No more regular LFT Monitoring ...

... Oral Hypoglycemics TZD Lipid Effects Rosiglitazone (Avandia) +LDL +HDL +Triglycerides Rosiglitazone Black box warning for CHF and ischemic heart disease; ...

Some Things You May Be Interested In With Regard To Therapy for Type 2 Diabetes

Update in Diabetes Management Oral Therapies. Amy M. Lugo, PharmD, BCPS, CDM ... Use in premenopausal anovulatory women may cause resumption of ovulation ...

Diabetes Mellitus Normal Insulin Synthesis Prosinsulin is produced in the beta cells Before secretion, prosinsulin cleaved into Insulin Connecting peptide (aka C ...

1.Patients with type 2 diabetes are at high risk of fatal and non ... intermittent claudication with an ankle or toe brachial pressure index of less than 0 9 ...

Dr. Thomas Iype Medical College Thiruvananthapuram Vajda FJ, O Brien TJ, Hitchcock A, Graham J, Cook M, Lander C, Eadie MJ. (2004) Critical relationship between ...

Diabetes Change Agent A National Pilot Program * * * * Amylin is absolutely or relatively deficient in DM Deficiency in amylin results in more fluctuations with blood ...

Managing the Patient with Diabetes Cindy Brown, RN, MN, ANP, CDE Introduction Scope of the problem Number of people with Type 2 diabetes approaches 21 million One ...

Diabetes Mellitus Overview and Treatments Andrew P. Vogt Chemistry 6116 Diabetes Mellitus : a group of diseases characterized by high levels of blood glucose ...

In the 12 studies of kidney transplantation, ... peripheral tissue insulin sensitivity Related to the dose and the duration of therapy Calcineurin inhibitor ...